product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human CCND2 protein
catalog :
ATGP1342
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human CCND2 protein
Domain :
1-289aa
Catalog number (SKU) :
ATGP1342
NCBI :
NP_001750
Description :
CCND2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. High level expression of this protein was observed in ovarian and testicular tumors. Recombinant human CCND2 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Alternative Names :
Cyclin D2, KIAK0002, MGC102758, G1/S-specific cyclin-D2
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 1M urea.
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Inaba T., et al. (1992) Genomics. 13(3):565-74.;; Wang Z., et al. (2008) Cell Struct Funct. 33(2):171-83.
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Cancer
Molecular Weight :
35.6 kDa (313aa)
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSHMELLCH EVDPVRRAVR DRNLLRDDRV LQNLLTIEER YLPQCSYFKC VQKDIQPYMR RMVATWMLEV CEEQKCEEEV FPLAMNYLDR FLAGVPTPKS HLQLLGAVCM FLASKLKETS PLTAEKLCIY TDNSIKPQEL LEWELVVLGK LKWNLAAVTP HDFIEHILRK LPQQREKLSL IRKHAQTFIA LCATDFKFAM YPPSMIATGS VGAAICGLQQ DEEVSSLTCD ALTELLAKIT NTDVDCLKAC QEQIEAVLLN SLQQYRQDQR DGSKSEDELD QASTPTDVRD IDL
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P30279
Internal Search Terms :
CCND2, Cyclin D2, KIAK0002, MGC102758, G1/S-specific cyclin-D2,ATGP1342-10ug,ATGP1342-20ug,ATGP1342-50ug,ATGP1342-100ug,ATGP1342-250ug,ATGP1342-500ug,ATGP1342-1mg,ATGP1342-10,ATGP1342-20,ATGP1342-50,ATGP1342-100,ATGP1342-250,ATGP1342-500,ATGP1342-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.