product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human Histone Deacetylase 8/HDAC8 protein
catalog :
ATGP1329
quantity :
10 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human Histone Deacetylase 8/HDAC8 protein
Domain :
1-377aa
Catalog number (SKU) :
ATGP1329
NCBI :
NP_060956
Description :
HDAC8, also known as histone deacetylase 8, belongs to class 1 of the histone deacetylase/acuc/apha family. This protein is biologically involved in skull morphogenesis and metabolic control of the ERR-alpha/PGC1-alpha transcriptional complex. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Recombinant human HDAC8 protein, fused to His-tag at C-terminus, was expressed in Sf9 insect cell and purified by using conventional chromatography.
Alternative Names :
Protein deacetylase HDAC8, Protein decrotonylase HDAC8, Wilson-Turner X-linked mental retardation syndrome HDACL1, CDA07, WTS, MRXS6, RPD3, KDAC8
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Hu E., et al. (2000) J. Biol. Chem. 275:15254-15264;; Buggy J.J., et al. (2000) Biochem. J. 350:199-205
Purity :
> 80% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Epigenomics (Transcription & Translation)
Molecular Weight :
42.6 kDa (383aa)
Endotoxin :
<1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
MEEPEEPADS GQSLVPVYIY SPEYVSMCDS LAKIPKRASM VHSLIEAYAL HKQMRIVKPK VASMEEMATF HTDAYLQHLQ KVSQEGDDDH PDSIEYGLGY DCPATEGIFD YAAAIGGATI TAAQCLIDGM CKVAINWSGG WHHAKKDEAS GFCYLNDAVL GILRLRRKFE RILYVDLDLH HGDGVEDAFS FTSKVMTVSL HKFSPGFFPG TGDVSDVGLG KGRYYSVNVP IQDGIQDEKY YQICESVLKE VYQAFNPKAV VLQLGADTIA GDPMCSFNMT PVGIGKCLKY ILQWQLATLI LGGGGYNLAN TARCWTYLTG VILGKTLSSE IPDHEFFTAY GPDYVLEITP SCRPDRNEPH RIQQILNYIK GNLKHVV
Tag :
His-Tag
Expression System :
Baculovirus
Product Type Name :
Recombinant Protein
UniProt No. :
Q9BY41
Internal Search Terms :
Histone Deacetylase8, Histone deacetylase 8, CDA07, HD8, HDACL1, RPD3,ATGP1329-10ug,ATGP1329-20ug,ATGP1329-50ug,ATGP1329-100ug,ATGP1329-250ug,ATGP1329-500ug,ATGP1329-1mg,ATGP1329-10,ATGP1329-20,ATGP1329-50,ATGP1329-100,ATGP1329-250,ATGP1329-500,ATGP1329-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.