Recombinant human p38 beta/MAPK11 protein | NKMAX ATGP1299 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human p38 beta/MAPK11 protein

catalog :

ATGP1299

quantity :

10 ug

price :

150 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human p38 beta/MAPK11 protein

Domain :

1-364aa

Catalog number (SKU) :

ATGP1299

NCBI :

NP_002742.3

Description :

MAPK11 (Mitogen-activated protein kinase 11) is a member of the MAP kinase family. This kinase is most closely related to p38 MAP kinases (MAPKs). MAPKs are activated primarily in response to inflammatory cytokines and cellular stress, and inhibitors which target the MAPK14 and MAPK11 have shown potential for the treatment of inflammatory disease. MAPK11 has been shown to interact with HDAC3 and Promyelocytic leukemia protein. This kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. Recombinant human MAPK11 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Mitogen-activated protein kinase 11, p38-2, P38B, p38Beta, P38BETA2, PRKM11, SAPK2, SAPK2B

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 100mM NaCl

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Beardmore VA, et al. (2005) Mol Cell Biol. 25(23):10454-64.;; Mahlknecht u, et al. (2004) J Immunol. 173(6):3979-90.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

43.7 kDa (387aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MSGPRAG FYRQELNKTV WEVPQRLQGL RPVGSGAYGS VCSAYDARLR QKVAVKKLSR PFQSLIHARR TYRELRLLKH LKHENVIGLL DVFTPATSIE DFSEVYLVTT LMGADLNNIV KCQALSDEHV QFLVYQLLRG LKYIHSAGII HRDLKPSNVA VNEDCELRIL DFGLARQADE EMTGYVATRW YRAPEIMLNW MHYNQTVDIW SVGCIMAELL QGKALFPGSD YIDQLKRIME VVGTPSPEVL AKISSEHART YIQSLPPMPQ KDLSSIFRGA NPLAIDLLGR MLVLDSDQRV SAAEALAHAY FSQYHDPEDE PEAEPYDESV EAKERTLEEW KELTYQEVLS FKPPEPPKPP GSLEIEQ

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q15759

Internal Search Terms :

p38 b, MAPK11, Mitogen-activated protein kinase 11, p38-2, P38B, p38Beta, P38BETA2, PRKM11, SAPK2, SAPK2B,ATGP1299-10ug,ATGP1299-20ug,ATGP1299-50ug,ATGP1299-100ug,ATGP1299-250ug,ATGP1299-500ug,ATGP1299-1mg,ATGP1299-10,ATGP1299-20,ATGP1299-50,ATGP1299-100,ATGP1299-250,ATGP1299-500,ATGP1299-1

more info or order :

NKMAX product webpage