product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human RAB23 protein
catalog :
ATGP1290
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human RAB23 protein
Domain :
1-234aa
Catalog number (SKU) :
ATGP1290
NCBI :
NP_057361
Description :
RAB23, also known as ras-related protein Rab23, is a member of the Rab family of proteins and localizes to the cytoplasmic side of the cell membrane. This protein is thought to to play a role in intracellular protein transportation and signal transduction mediated by small GTPases. RAB23 is an essential negative regulator of the Sonic hedgehog signaling pathway. Mutations in the gene encoding RAB23 may result in Carpenter syndrome a condition characterized by obesity, cardiac defects, polysyndactyly and craniosynostosis. Recombinant human RAB23 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Alternative Names :
Ras-related protein Rab-23, DKFZp781H0695, HSPC137, MGC8900, RAB23 member RAS oncogene family
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 30% glycerol, 1mM DTT, 0.1mM PMSF
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Marcos I. et al. (2003) Int J Mol Med. 12:983-987.;; Eggenschwiler JT. et al. (2001) Nature. 412:194-198.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Signal Transduction
Molecular Weight :
28.5 kDa (254aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MLEEDMEVAI KMVVVGNGAV GKSSMIQRYC KGIFTKDYKK TIGVDFLERQ IQVNDEDVRL MLWDTAGQEE FDAITKAYYR GAQACVLVFS TTDRESFEAV SSWREKVVAE VGDIPTVLVQ NKIDLLDDSC IKNEEAEALA KRLKLRFYRT SVKEDLNVNE VFKYLAEKYL QKLKQQIAED PELTHSSSNK IGVFNTSGGS HSGQNSGTLN GGDVINLRPN KQRTKKNRNP FSSC
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q9ULC3
Internal Search Terms :
RAB23, Ras-related protein Rab-23, DKFZp781H0695, HSPC137, MGC8900,ATGP1290-10ug,ATGP1290-20ug,ATGP1290-50ug,ATGP1290-100ug,ATGP1290-250ug,ATGP1290-500ug,ATGP1290-1mg,ATGP1290-10,ATGP1290-20,ATGP1290-50,ATGP1290-100,ATGP1290-250,ATGP1290-500,ATGP1290-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.