product summary
Loading...
company name :
NKMAX
product type :
protein
product name :
Recombinant human GMDS protein
catalog :
ATGP1282
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human GMDS protein
Domain :
1-372aa
Catalog number (SKU) :
ATGP1282
NCBI :
NP_001491
Description :
GMDS, also known as SDR3E1, belongs to the GDP-mannose 4, 6-dehydratase family. This protein utilizes NADP as a cofactor to catalyze the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose. Mutations in the gene encoding GMDS are involved in resistance to TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) -induced apoptosis. Recombinant human GMDS protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Alternative Names :
GDP-mannose 46 dehydratase, GDP-mannose 4,6 dehydratase, GMD, SDR3E1
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 30% glycerol, 0.1M NaCl,1mM DTT, 0.1mM PMSF
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Ohyama C. et al. (1998) J Biol Chem. 273: 14582-14587.;; Moriwaki K. et al. (2009) Gastroenterology 137: 188-198.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Metabolism
Molecular Weight :
44.1 kDa (392aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MAHAPARCPS ARGSGDGEMG KPRNVALITG ITGQDGSYLA EFLLEKGYEV HGIVRRSSSF NTGRIEHLYK NPQAHIEGNM KLHYGDLTDS TCLVKIINEV KPTEIYNLGA QSHVKISFDL AEYTADVDGV GTLRLLDAVK TCGLINSVKF YQASTSELYG KVQEIPQKET TPFYPRSPYG AAKLYAYWIV VNFREAYNLF AVNGILFNHE SPRRGANFVT RKISRSVAKI YLGQLECFSL GNLDAKRDWG HAKDYVEAMW LMLQNDEPED FVIATGEVHS VREFVEKSFL HIGKTIVWEG KNENEVGRCK ETGKVHVTVD LKYYRPTEVD FLQGDCTKAK QKLNWKPRVA FDELVREMVH ADVELMRTNP NA
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
O60547
Internal Search Terms :
GMDS,ATGP1282-10ug,ATGP1282-20ug,ATGP1282-50ug,ATGP1282-100ug,ATGP1282-250ug,ATGP1282-500ug,ATGP1282-1mg,ATGP1282-10,ATGP1282-20,ATGP1282-50,ATGP1282-100,ATGP1282-250,ATGP1282-500,ATGP1282-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.