Recombinant human MafG protein | NKMAX ATGP1268 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human MafG protein

catalog :

ATGP1268

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human MafG protein

Domain :

1-162aa

Catalog number (SKU) :

ATGP1268

NCBI :

NP_116100.2

Description :

MAFG, also known as transcription factor MafG, belongs to the Maf family. Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Recombinant human MAFG protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Alternative Names :

Transcription factor MafG, hMAF, MAFG, V-maf musculoaponeurotic fibrosarcoma oncogene homolog G

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Hung H.-L., et al. (2001) J. Biol. Chem. 276:10715-10721;; Blank V., et al. (1997) Genomics. 44:147-149

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

20 kDa (182aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MTTPNKGNKA LKVKREPGEN GTSLTDEELV TMSVRELNQH LRGLSKEEIV QLKQRRRTLK NRGYAASCRV KRVTQKEELE KQKAELQQEV EKLASENASM KLELDALRSK YEALQTFART VARSPVAPAR GPLAAGLGPL VPGKVAATSV ITIVKSKTDA RS

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O15525

Internal Search Terms :

MafG, Transcription factor MafG, hMAF,ATGP1268-10ug,ATGP1268-20ug,ATGP1268-50ug,ATGP1268-100ug,ATGP1268-250ug,ATGP1268-500ug,ATGP1268-1mg,ATGP1268-10,ATGP1268-20,ATGP1268-50,ATGP1268-100,ATGP1268-250,ATGP1268-500,ATGP1268-1

References with this Product :

Lacher SE, et al. Beyond antioxidant genes in the ancient NRF2 regulatory network. (Free Radic Biol Med. 2015){https://pubmed.ncbi.nlm.nih.gov/26163000/};; Lacher SE, et al. A hypermorphic antioxidant response element is associated with increased MS4A6A expression and Alzheimers disease. (Redox Biol. 2018){https://pubmed.ncbi.nlm.nih.gov/29179108/};; Lacher SE, et al. An antioxidant response element regulates the HIF1α axis in breast cancer cells. (Free Radic Biol Med. 2023){https://pubmed.ncbi.nlm.nih.gov/37179033/}

more info or order :

NKMAX product webpage