Recombinant human p27/Kip1 protein | NKMAX ATGP1264 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human p27/Kip1 protein

catalog :

ATGP1264

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human p27/Kip1 protein

Domain :

1-198aa

Catalog number (SKU) :

ATGP1264

NCBI :

NP_004055.1

Description :

CDKN1B, also known as cyclin-dependent kinase inhibitor 1B, belongs to the Cip/Kip family of cyclin dependent kinase (Cdk) inhibitor proteins. This protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. It is often referred to as a cell cycle inhibitor protein because its major function is to stop or slow down the cell division cycle. Recombinant human CDKN1B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Alternative Names :

Cyclin-dependent kinase inhibitor 1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Ishida N., et al. (2000) J. Biol. Chem. 275:25146-25154;; Viglietto G., et al. (2002) Nat. Med. 8:1136-1144

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cell Cycle

Molecular Weight :

24.2 kDa (218aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Amino Acid Sequence :

MSNVRVSNGS PSLERMDARQ AEHPKPSACR NLFGPVDHEE LTRDLEKHCR DMEEASQRKW NFDFQNHKPL EGKYEWQEVE KGSLPEFYYR PPRPPKGACK VPAQESQDVS GSRPAAPLIG APANSEDTHL VDPKTDPSDS QTGLAEQCAG IRKRPATDDS STQNKRANRT EENVSDGSPN AGSVEQTPKK PGLRRRQT

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P46527

Internal Search Terms :

p27, Kip1, Cyclin-dependent kinase inhibitor 1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1,ATGP1264-10ug,ATGP1264-20ug,ATGP1264-50ug,ATGP1264-100ug,ATGP1264-250ug,ATGP1264-500ug,ATGP1264-1mg,ATGP1264-10,ATGP1264-20,ATGP1264-50,ATGP1264-100,ATGP1264-250,ATGP1264-500,ATGP1264-1

more info or order :

NKMAX product webpage