Recombinant human GITR Ligand/TNFSF18 protein | NKMAX ATGP1249 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human GITR Ligand/TNFSF18 protein

catalog :

ATGP1249

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human GITR Ligand/TNFSF18 protein

Domain :

72-199aa

Catalog number (SKU) :

ATGP1249

NCBI :

NP_005083

Description :

TNFSF18, also known as GITRL, belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It is Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. Recombinant human TNFSF18 protein was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Alternative Names :

Activation-inducible TNF-related ligand, AITRL, GITRL, Glucocorticoid-induced TNF-related ligand, hGITRL, TL6, TNF superfamily member 18, Tumor necrosis factor (ligand) superfamily member 18

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 10mM Sodium Citrate buffer (pH 3.5) containing 1mM DTT, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Kwon B, et al. (1999) J Biol Chem 274 (10): 6056-61.;; Gurney AL, et al. (1999). Curr Biol 9 (4): 215-8.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Hormones & Cytokines

Molecular Weight :

14.6 kDa (129aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MQLETAKEPC MAKFGPLPSK WQMASSEPPC VNKVSDWKLE ILQNGLYLIY GQVAPNANYN DVAPFEVRLY KNKDMIQTLT NKSKIQNVGG TYELHVGDTI DLIFNSEHQV LKNNTYWGII LLANPQFIS

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9UNG2

Internal Search Terms :

GITR Ligand, TNFSF18, Tumor necrosis factor (ligand) superfamily member 18, AITRL, TL6, GITRL, hGITRL,ATGP1249-10ug,ATGP1249-20ug,ATGP1249-50ug,ATGP1249-100ug,ATGP1249-250ug,ATGP1249-500ug,ATGP1249-1mg,ATGP1249-10,ATGP1249-20,ATGP1249-50,ATGP1249-100,ATGP1249-250,ATGP1249-500,ATGP1249-1

more info or order :

NKMAX product webpage