Recombinant human RAB24 protein | NKMAX ATGP1247 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human RAB24 protein

catalog :

ATGP1247

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human RAB24 protein

Domain :

1-203aa

Catalog number (SKU) :

ATGP1247

NCBI :

NP_570137

Description :

RAB24 belongs to the small GTPase superfamily. Members of the Rab GTPase family regulate intracellular protein trafficking, but the specific function of RAB24 remains unknown. RAB24 is distributed in the endoplasmic reticulum/cis-Golgi region and on late endosomal structures, and this subcellular distribution pattern of RAB24 may indicate its involvement in autophagy-related processes. RAB24 presents unusual characteristics, including low intrinsic GTPase activity, and is inefficiently prenylated when compared with other Rab proteins. Also suggested that RAB24 might play a unique role in the degradation of misfolded cellular proteins or trafficking of proteins to the nuclear envelope. Recombinant human RAB24 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Ras-related protein Rab-24, RAB24 member RAS oncogene family

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 30% glycerol, 100mM NaCl, 1mM EDTA

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Maltese WA, et al. (2002) BMC Cell Biol. 3:25.;; Wu M, Yin G, et al. (2006) Int J Mol Med. 17(5):749-54.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

25.6 kDa (227aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MSGQRV DVKVVMLGKE YVGKTSLVER YVHDRFLVGP YQNTIGAAFV AKVMSVGDRT VTLGIWDTAG SERYEAMSRI YYRGAKAAIV CYDLTDSSSF ERAKFWVKEL RSLEEGCQIY LCGTKSDLLE EDRRRRRVDF HDVQDYADNI KAQLFETSSK TGQSVDELFQ KVAEDYVSVA AFQVMTEDKG VDLGQKPNPY FYSCCHH

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q969Q5

Internal Search Terms :

RAB24, Ras-related protein Rab-24,ATGP1247-10ug,ATGP1247-20ug,ATGP1247-50ug,ATGP1247-100ug,ATGP1247-250ug,ATGP1247-500ug,ATGP1247-1mg,ATGP1247-10,ATGP1247-20,ATGP1247-50,ATGP1247-100,ATGP1247-250,ATGP1247-500,ATGP1247-1

more info or order :

NKMAX product webpage