product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human LAT protein
catalog :
ATGP1238
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human LAT protein
Domain :
28-233aa
Catalog number (SKU) :
ATGP1238
NCBI :
NP_001014987
Description :
LAT is an integral membrane protein which is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. LAT is expressed in T lymphocytes in interstitial spaces, platelets and megakaryocytes. LAT is not expressed in B cells, macrophages, plasma cells, monocytes, epithelial histiocytes and dendritic cells. Recombinant human LAT protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
linker for activation of T-cells family member 1 isoform b, LAT1, pp36
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Paz PE., et al. (2001) Biochem J. 356(2):461-71.;; Zhang W., et al. (1998) Cell. 92(1):83-92.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Signal Transduction
Molecular Weight :
24.4 kDa (227aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Amino Acid Sequence :
HCHRLPGSY DSTSSDSLYP RGIQFKRPHT VAPWPPAYPP VTSYPPLSQP DLLPIPRSPQ PLGGSHRTPS SRRDSDGANS VASYENEEPA CEDADEDEDD YHNPGYLVVL PDSTPATSTA APSAPALSTP GIRDSAFSME SIDDYVNVPE SGESAEASLD GSREYVNVSQ ELHPGAAKTE PAALSSQEAE EVEEEGAPDY ENLQELN
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
O43561
Internal Search Terms :
LAT, linker for activation of T-cells family member 1 isoform b, LAT1, pp36,ATGP1238-10ug,ATGP1238-20ug,ATGP1238-50ug,ATGP1238-100ug,ATGP1238-250ug,ATGP1238-500ug,ATGP1238-1mg,ATGP1238-10,ATGP1238-20,ATGP1238-50,ATGP1238-100,ATGP1238-250,ATGP1238-500,ATGP1238-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.