product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human PSMB10/MECL1 protein
catalog :
ATGP1212
quantity :
10 ug
price :
160 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human PSMB10/MECL1 protein
Domain :
40-273aa
Catalog number (SKU) :
ATGP1212
NCBI :
NP_002792.1
Description :
PSMB10 is a member of the proteasome B-type family, also known as the T1B family, which is a 20S core beta subunit. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. Expression of the PSMB10 gene is induced by gamma interferon, and PSMB10 replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. Recombinant human PSMB10 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Alternative Names :
Proteasome subunit beta type-10, LMP10, MECL1
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.1M NaCl
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Foss G.S., et al. (1998) Biochim. Biophys. Acta. 1402:17-28;; Hisamatsu H., et al. (1996) J. Exp. Med. 183:1807-1816
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
26.9 kDa (255aa) confirmed by MALDI-TOF
Amino Acid Sequence :
TTIAGLVFQ DGVILGADTR ATNDSVVADK SCEKIHFIAP KIYCCGAGVA ADAEMTTRMV ASKMELHALS TGREPRVATV TRILRQTLFR YQGHVGASLI VGGVDLTGPQ LYGVHPHGSY SRLPFTALGS GQDAALAVLE DRFQPNMTLE AAQGLLVEAV TAGILGDLGS GGNVDACVIT KTGAKLLRTL SSPTEPVKRS GRYHFVPGTT AVLTQTVKPL TLELVEETVQ AMEVE
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P40306
Internal Search Terms :
PSMB10, MECL1, Proteasome subunit beta type-10, LMP10, MECL1,ATGP1212-10ug,ATGP1212-20ug,ATGP1212-50ug,ATGP1212-100ug,ATGP1212-250ug,ATGP1212-500ug,ATGP1212-1mg,ATGP1212-10,ATGP1212-20,ATGP1212-50,ATGP1212-100,ATGP1212-250,ATGP1212-500,ATGP1212-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.