protein

Recombinant human FLIP protein

ATGP1195

20 ug

80 USD

Recombinant human FLIP protein

1-480aa

ATGP1195

NP_003870

CFLAR, also known as FLIP, is involved in the regulation of apoptosis. It has been designated by independent groups as Casper, I-FLICE, CLARP, FLAME-1 and MRIT. Although its exact role is still being elucidated, it appears to be an important factor in the regulation of apoptosis downstream of all known death receptors. Recombinant human CFLAR protein was expressed in E. coli and denatured using detergent during a conventional chromatography purification process.

CASP8 and FADD-like apoptosis regulator, CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, uSuRPIN

1mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Hu S. et al. (1997) J Biol Chem. 272: 17255-17257.;; Thome M. et al. (1997). Nature 386: 517-521

> 85% by SDS-PAGE

SDS-PAGE,Denatured

Human

Apoptosis

55.3 kDa (480aa)

MSAEVIHQVE EALDTDEKEM LLFLCRDVAI DVVPPNVRDL LDILRERGKL SVGDLAELLY RVRRFDLLKR ILKMDRKAVE THLLRNPHLV SDYRVLMAEI GEDLDKSDVS SLIFLMKDYM GRGKISKEKS FLDLVVELEK LNLVAPDQLD LLEKCLKNIH RIDLKTKIQK YKQSVQGAGT SYRNVLQAAI QKSLKDPSNN FRLHNGRSKE QRLKEQLGAQ QEPVKKSIQE SEAFLPQSIP EERYKMKSKP LGICLIIDCI GNETELLRDT FTSLGYEVQK FLHLSMHGIS QILGQFACMP EHRDYDSFVC VLVSRGGSQS VYGVDQTHSG LPLHHIRRMF MGDSCPYLAG KPKMFFIQNY VVSEGQLENS SLLEVDGPAM KNVEFKAQKR GLCTVHREAD FFWSLCTADM SLLEQSHSSP SLYLQCLSQK LRQERKRPLL DLHIELNGYM YDWNSRVSAK EKYYVWLQHT LRKKLILSYT

Non-Tagged

E.coli

Recombinant Protein

O15519

FLIP, CASP8 and FADD-like apoptosis regulator, CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, uSuRPIN,ATGP1195-10ug,ATGP1195-20ug,ATGP1195-50ug,ATGP1195-100ug,ATGP1195-250ug,ATGP1195-500ug,ATGP1195-1mg,ATGP1195-10,ATGP1195-20,ATGP1195-50,ATGP1195-100,ATGP1195-250,ATGP1195-500,ATGP1195-1