product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human Cofilin 2/CFL2 protein
catalog :
ATGP1183
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human Cofilin 2/CFL2 protein
Domain :
1-166aa
Catalog number (SKU) :
ATGP1183
NCBI :
NP_068733
Description :
CFL2 protein belongs to the actin-binding proteins ADF family that contains 1 ADF-H domain. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. Defects in CFL2 are the cause of nemaline myopathy type 7 (NEM7). Recombinant human CFL2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
CFL2, Cofilin 2, NEM7
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 50mM Nacl
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Agrawal P.B., et al. (2007) Am. J. Hum. Genet. 80:162-167;; Gillett GT, et al. (1996). Ann. Hum. Genet. 60 (Pt 3): 201-11
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Cytoskeleton
Molecular Weight :
20.9 kDa (186a) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MASGVTVNDE VIKVFNDMKV RKSSTQEEIK KRKKAVLFCL SDDKRQIIVE EAKQILVGDI GDTVEDPYTS FVKLLPLNDC RYALYDATYE TKESKKEDLV FIFWAPESAP LKSKMIYASS KDAIKKKFTG IKHEWQVNGL DDIKDRSTLG EKLGGNVVVS LEGKPL
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q9Y281
Internal Search Terms :
CFL2, CFL 2, CFL-2, Cofilin2, Cofilin 2, Cofilin-2, NEM7, ATGP1183-10ug, ATGP1183-20ug, ATGP1183-50ug, ATGP1183-100ug, ATGP1183-250ug, ATGP1183-500ug, ATGP1183-1mg, ATGP1183-010, ATGP1183-020, ATGP1183-050, ATGP1183-100, ATGP1183-250, ATGP1183-500, ATGP1183-01M
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.