Recombinant human CDK2 protein | NKMAX ATGP1180 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CDK2 protein

catalog :

ATGP1180

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CDK2 protein

Domain :

1-298aa

Catalog number (SKU) :

ATGP1180

NCBI :

NP_001789.2

Description :

CDK2, also known as cyclin-depentent kinase 2, is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and is essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by protein phosphorylation. Recombinant human CDK2 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography.

Alternative Names :

Cyclin-depentent kinase 2, p33, CDK2

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Gyuris J., et al. (1993) Cell. 75:791-803;; Hannon G.J., et al. (1994) Proc. Natl. Acad. Sci. u.S.A. 91:1731-1735

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

35.0 kDa (306aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MENFQKVEKI GEGTYGVVYK ARNKLTGEVV ALKKIRLDTE TEGVPSTAIR EISLLKELNH PNIVKLLDVI HTENKLYLVF EFLHQDLKKF MDASALTGIP LPLIKSYLFQ LLQGLAFCHS HRVLHRDLKP QNLLINTEGA IKLADFGLAR AFGVPVRTYT HEVVTLWYRA PEILLGCKYY STAVDIWSLG CIFAEMVTRR ALFPGDSEID QLFRIFRTLG TPDEVVWPGV TSMPDYKPSF PKWARQDFSK VVPPLDEDGR SLLSQMLHYD PNKRISAKAA LAHPFFQDVT KPVPHLRL

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P24941

Internal Search Terms :

CDK2, Cyclin-depentent kinase 2, p33, CDK2,ATGP1180-10ug,ATGP1180-20ug,ATGP1180-50ug,ATGP1180-100ug,ATGP1180-250ug,ATGP1180-500ug,ATGP1180-1mg,ATGP1180-10,ATGP1180-20,ATGP1180-50,ATGP1180-100,ATGP1180-250,ATGP1180-500,ATGP1180-1

more info or order :

NKMAX product webpage