product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human CLF-1/CLC protein
catalog :
ATGP1179
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human CLF-1/CLC protein
Domain :
28-225aa
Catalog number (SKU) :
ATGP1179
NCBI :
NP_037378
Description :
CLCF1, also known as cardiotrophin-like cytokine factor 1, belongs to the interleukin 6 family of cytokines, which are involved in cell signaling through phosphorylation of gp130. CLCF1 has a sequence of 225-amino acids with a 27-aa signal peptide, a molecular mass of 22 kDa in mature form, and the highest homology to cardiotrophin-1 and ciliary neurotrophic factor. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine.
Alternative Names :
Cardiotrophin-like cytokine factor 1, BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM sodium citrate (pH 3.5) 0.4M urea, 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Senaldi G., et al. (1999) Proc. Natl. Acad. Sci. u.S.A. 96:11458-11463;; Shi Y., et al. (1999) Biochem. Biophys. Res. Commun. 262:132-138
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE,Denatured
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
24.6 kDa (219aa)
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MLNRTGDPGP GPSIQKTYDL TRYLEHQLRS LAGTYLNYLG PPFNEPDFNP PRLGAETLPR ATVDLEVWRS LNDKLRLTQN YEAYSHLLCY LRGLNRQAAT AELRRSLAHF CTSLQGLLGS IAGVMAALGY PLPQPLPGTE PTWTPGPAHS DFLQKMDDFW LLKELQTWLW RSAKDFNRLK KKMQPPAAAV TLHLGAHGF
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q9UBD9
Internal Search Terms :
CLF1, CLC, Cardiotrophin-like cytokine factor 1, BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6,ATGP1179-10ug,ATGP1179-20ug,ATGP1179-50ug,ATGP1179-100ug,ATGP1179-250ug,ATGP1179-500ug,ATGP1179-1mg,ATGP1179-10,ATGP1179-20,ATGP1179-50,ATGP1179-100,ATGP1179-250,ATGP1179-500,ATGP1179-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.