Recombinant human RGS10 protein | NKMAX ATGP1144 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human RGS10 protein

catalog :

ATGP1144

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human RGS10 protein

Domain :

1-181aa

Catalog number (SKU) :

ATGP1144

NCBI :

NP_001005339

Description :

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 (RGS10) belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. RGS10 protein is localized in the nucleus. Recombinant human RGS10 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Regulator of G-protein signaling 10, Regulator of G protein signaling 10

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Cali J J., et al. (1992) J Biol Chem. 267:24023-24027.;; Simon M I., et al. (1991) Science. 252:802-808.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

23.7 kDa (205aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSHMFNRAV SRLSRKRPPS DIHDSDGSSS SSHQSLKSTA KWAASLENLL EDPEGVKRFR EFLKKEFSEE NVLFWLACED FKKMQDKTQM QEKAKEIYMT FLSSKASSQV NVEGQSRLNE KILEEPHPLM FQKLQDQIFN LMKYDSYSRF LKSDLFLKHK RTEEEEEDLP DAQTAAKRAS RIYNT

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O43665

Internal Search Terms :

RGS10, Regulator of G-protein signaling 10, Regulator of G protein signaling 10,ATGP1144-10ug,ATGP1144-20ug,ATGP1144-50ug,ATGP1144-100ug,ATGP1144-250ug,ATGP1144-500ug,ATGP1144-1mg,ATGP1144-10,ATGP1144-20,ATGP1144-50,ATGP1144-100,ATGP1144-250,ATGP1144-500,ATGP1144-1

more info or order :

NKMAX product webpage