product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human SHC1 protein
catalog :
ATGP1128
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human SHC1 protein
Domain :
1-474aa
Catalog number (SKU) :
ATGP1128
NCBI :
NP_003020
Description :
SHC1 (SHC-transforming protein 1) belongs to the SH2 domain family. SHC1 has been found to be important in the regulation of apoptosis and drug resistance in mammalian cells. It is a signaling adapter that couples activated growth factor receptors to signaling pathway. SHC1 expressed in neural stem cells but absent in mature neurons. Recombinant human SHC1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
SHC-transforming protein 1, FLJ26504, SH2 domain protein C1, SHC, SHC-transforming protein 3, p66, MGC98812, SHCA, Src homology 2 domain containing transforming protein C1
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 200mM NaCl, 0.1mM PMSF
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Debnath J., et al. (2010) Oncogene. 29(41):5556-8.;; Zhou M.-M., et al. (1995) Proc. Natl. Acad. Sci. u.S.A. 92:7784-7788
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Neuroscience
Molecular Weight :
53.8 kDa (494aa)
Amino Acid Sequence :
MNKLSGGGGR RTRVEGGQLG GEEWTRHGSF VNKPTRGWLH PNDKVMGPGV SYLVRYMGCV EVLQSMRALD FNTRTQVTRE AISLVCEAVP GAKGATRRRK PCSRPLSSIL GRSNLKFAGM PITLTVSTSS LNLMAADCKQ IIANHHMQSI SFASGGDPDT AEYVAYVAKD PVNQRACHIL ECPEGLAQDV ISTIGQAFEL RFKQYLRNPP KLVTPHDRMA GFDGSAWDEE EEEPPDHQYY NDFPGKEPPL GGVVDMRLRE GAAPGAARPT APNAQTPSHL GATLPVGQPV GGDPEVRKQM PPPPPCPAGR ELFDDPSYVN VQNLDKARQA VGGAGPPNPA INGSAPRDLF DMKPFEDALR VPPPPQSVSM AEQLRGEPWF HGKLSRREAE ALLQLNGDFL VRESTTTPGQ YVLTGLQSGQ PKHLLLVDPE GVVRTKDHRF ESVSHLISYH MDNHLPIISA GSELCLQQPV ERKL
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P29353
Internal Search Terms :
SHC1, SHC-transforming protein 1, FLJ26504, SH2 domain protein C1, SHC, SHC-transforming protein 3, p66, MGC98812, SHCA, Src homology 2 domain containing transforming protein C1,ATGP1128-10ug,ATGP1128-20ug,ATGP1128-50ug,ATGP1128-100ug,ATGP1128-250ug,ATGP1128-500ug,ATGP1128-1mg,ATGP1128-10,ATGP1128-20,ATGP1128-50,ATGP1128-100,ATGP1128-250,ATGP1128-500,ATGP1128-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.