Recombinant human ATF3 protein | NKMAX ATGP1127 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human ATF3 protein

catalog :

ATGP1127

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

citations: 1

Reference
Sato A, Nakama K, Watanabe H, Satake A, Yamamoto A, Omi T, et al. Role of activating transcription factor 3 protein ATF3 in necrosis and apoptosis induced by 5-fluoro-2'-deoxyuridine. FEBS J. 2014;281:1892-900 pubmed publisher

product information

Product Type :

Proteins

Item Name :

Recombinant human ATF3 protein

Domain :

1-181aa

Catalog number (SKU) :

ATGP1127

NCBI :

NP_001665

Description :

ATF3 (activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription, it is presumed, by sequestering inhibitory co-factors away from the promoter.

Alternative Names :

Activating transcription factor 3, ATF3deltaZip3, cAMP dependent transcription factor ATF3, Cyclic AMP dependent transcription factor ATF3, Cyclic AMP-dependent transcription factor ATF-3

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Lv D., et al. (2011) IuBMB Life. 63(1):62-9. ;; Chen BP., et al. (1994) J Biol Chem 269 (22): 15819-26.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

20.6 kDa (181aa)

Amino Acid Sequence :

MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P18847

Internal Search Terms :

ATF3, Activating transcription factor 3, ATF3deltaZip2, ATF3deltaZip2c, ATF3deltaZip3, cAMP dependent transcription factor ATF3, Cyclic AMP dependent transcription factor ATF3, Cyclic AMP-dependent transcription factor ATF-3,ATGP1127-10ug,ATGP1127-20ug,ATGP1127-50ug,ATGP1127-100ug,ATGP1127-250ug,ATGP1127-500ug,ATGP1127-1mg,ATGP1127-10,ATGP1127-20,ATGP1127-50,ATGP1127-100,ATGP1127-250,ATGP1127-500,ATGP1127-1

References with this Product :

Sato A, et al. Role of activating transcription factor 3 protein ATF3 in necrosis and apoptosis induced by 5-fluoro-2-deoxyuridine. (FEBS J. 2014){https://pubmed.ncbi.nlm.nih.gov/24529083/}

more info or order :

NKMAX product webpage