protein

Recombinant mouse S100A9 protein

ATGP1120

10 ug

105 USD

Recombinant mouse S100A9 protein

1-113aa

ATGP1120

NP_033140.1

S100A9, also known as Calgranulin-B, belongs to the S100 family containing EF-hand type Ca2+-binding proteins. It is involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation, and associated with the disease cystic fibrosis. S100A9 has been implicated in the abnormal differentiation of myeloid cells in the stroma of cancer. This protein may function in the inhibition of casein kinase. Recombinant mouse S100A9 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

S100 calcium binding protein A9, Calgranulin-B, Cagb, Mrp14

0.5mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Schafer BW., et al. (1996) Trends biochem Sci. 21(4):134-140;; Nacken W., et al. (2003) Microsc Res Tech. 60:569-580

> 90% by SDS-PAGE

SDS-PAGE

Mouse

Signal Transduction

15.2 kDa (133aa) confirmed by MALDI-TOF

MANKAPSQME RSITTIIDTF HQYSRKEGHP DTLSKKEFRQ MVEAQLATFM KKEKRNEALI NDIMEDLDTN QDNQLSFEEC MMLMAKLIFA CHEKLHENNP RGHGHSHGKG CGK

His-Tag

E.coli

Recombinant Protein

P31725

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Takagi R, et al. S100A9 Increases IL-6 and RANKL Expressions through MAPKs and STAT3 Signaling Pathways in Osteocyte-Like Cells. (Biomed Res Int. 2020){https://pubmed.ncbi.nlm.nih.gov/32149126/}