protein

Recombinant mouse S100A8 protein

ATGP1085

20 ug

80 USD

Recombinant mouse S100A8 protein

1-89aa

ATGP1085

NP_038678

S100A8, also known MRP8, is a member of the S100 family, EF-hand superfamily of calcium binding proteins. This protein is localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. It functions both intracellularly and extracellularly, where it binds to RAGE and CD36. Altered expression of this protein is associated with the disease cystic fibrosis. Recombinant mouse S100A8 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Protein S100-A8, 60B8Ag, AI323541, B8Ag, Caga, CFAg, CP-10, MRP8, p8

1mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 30% glycerol, 0.1M NaCl,1mM DTT

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Kerkhoff C., et al. (1999) Biochim. Biophys. 1448(2):200-11. ;; Nacken W., et al. (2003) Biochim. Biophys. 60(6):569-80.

> 95% by SDS-PAGE

SDS-PAGE

Mouse

Cancer

12.4 kDa (109aa) confirmed by MALDI-TOF

MGSSHHHHHH SSGLVPRGSH MPSELEKALS NLIDVYHNYS NIQGNHHALY KNDFKKMVTT ECPQFVQNIN IENLFRELDI NSDNAINFEE FLAMVIKVGV ASHKDSHKE

His-Tag

E.coli

Recombinant Protein

P27005

S100A8, Protein S100-A8, 60B8Ag, AI323541, B8Ag, Caga, CFAg, CP-10, MRP8, p8,ATGP1085-10ug,ATGP1085-20ug,ATGP1085-50ug,ATGP1085-100ug,ATGP1085-250ug,ATGP1085-500ug,ATGP1085-1mg,ATGP1085-10,ATGP1085-20,ATGP1085-50,ATGP1085-100,ATGP1085-250,ATGP1085-500,ATGP1085-1

Takagi R, et al. S100A9 Increases IL-6 and RANKL Expressions through MAPKs and STAT3 Signaling Pathways in Osteocyte-Like Cells. (Biomed Res Int. 2020){https://pubmed.ncbi.nlm.nih.gov/32149126/}