product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human SNIP1 protein
catalog :
ATGP1071
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human SNIP1 protein
Domain :
258-396aa
Catalog number (SKU) :
ATGP1071
NCBI :
NP_078976
Description :
SNIP1 is smad nuclear interacting protein contains a forkhead-associated (FHA) domain and acts as a nuclear inhibitor of CBP/p300. This protein is an inhibitor of the TGF-beta signal transduction pathway and to be important in suppressing transcriptional activation dependent on the co-activators CBP and p300. Inhibition of NF-kappa B activity is a function of the N-terminal domain of SNIP1 and involves competition of SNIP1 and the NF-kappa B subunit, RelA/p65, for binding to p300, similar to the mechanism of inhibition of Smad signaling by SNIP1. Recombinant human SNIP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Smad nuclear interacting protein 1, FLJ12553, Splicing factor arginine/serine rich 4
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 100mM NaCl
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Kim RH, et al. (2000) Genes Dev. 14(13):1605-16.;; Kim RH, et al. (2001) J Biol Chem. 276(49):46297-304.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Epigenomics (Transcription & Translation)
Molecular Weight :
18.7 kDa (160aa) confirmed by MALDI-TOF
Amino Acid Sequence :
RWRLYPFKN DEVLPVMYIH RQSAYLLGRH RRIADIPIDH PSCSKQHAVF QYRLVEYTRA DGTVGRRVKP YIIDLGSGNG TFLNNKRIEP QRYYELKEKD VLKFGFSSRE YVLLHESSDT SEIDRKDDED EEEEEEVSDS
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q8TAD8
Internal Search Terms :
SNIP1, Smad nuclear interacting protein 1, FLJ12553, Splicing factor arginine/serine rich 4,ATGP1071-10ug,ATGP1071-20ug,ATGP1071-50ug,ATGP1071-100ug,ATGP1071-250ug,ATGP1071-500ug,ATGP1071-1mg,ATGP1071-10,ATGP1071-20,ATGP1071-50,ATGP1071-100,ATGP1071-250,ATGP1071-500,ATGP1071-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.