product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human UROS protein
catalog :
ATGP1066
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human UROS protein
Domain :
1-265aa
Catalog number (SKU) :
ATGP1066
NCBI :
NP_000366
Description :
uROS, also known as uroporphyrinogen III synthase, is an enzyme involved in the fourth step of porphyrin metabolism, involved in the conversion of hydroxymethyl bilane into uroporphyrinogen III. Defects in this protein can cause molecular lesions that lead to the autosomal recessive Gunther disease, also known as congenital erythropoietic porphyria (CEP). Recombinant human uROS protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Alternative Names :
uroporphyrinogen-III synthase, uroporphyrinogen III synthase
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Geronimi F. et al. (2003) J. Mol. Med. 81: 310-320.;; Omata Y. et al. (2004) J. BioChem. 136: 211-220.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Enzymes & Proteases
Molecular Weight :
30.7 kDa (285aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MKVLLLKDAK EDDCGQDPYI RELGLYGLEA TLIPVLSFEF LSLPSFSEKL SHPEDYGGLI FTSPRAVEAA ELCLEQNNKT EVWERSLKEK WNAKSVYVVG NATASLVSKI GLDTEGETCG NAEKLAEYIC SRESSALPLL FPCGNLKREI LPKALKDKGI AMESITVYQT VAHPGIQGNL NSYYSQQGVP ASITFFSPSG LTYSLKHIQE LSGDNIDQIK FAAIGPTTAR ALAAQGLPVS CTAESPTPQA LATGIRKALQ PHGCC
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P10746
Internal Search Terms :
UROS, uroporphyrinogen-III synthase, uroporphyrinogen III synthase,ATGP1066-10ug,ATGP1066-20ug,ATGP1066-50ug,ATGP1066-100ug,ATGP1066-250ug,ATGP1066-500ug,ATGP1066-1mg,ATGP1066-10,ATGP1066-20,ATGP1066-50,ATGP1066-100,ATGP1066-250,ATGP1066-500,ATGP1066-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.