product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human eIF-2B alpha/EIF2B1 protein
catalog :
ATGP1024
quantity :
10 ug
price :
240 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant human eIF-2B alpha/EIF2B1 protein
Domain :
1-305aa
Catalog number (SKU) :
ATGP1024
NCBI :
NP_001405
Description :
EIF2B1 is one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Phosphorylation of eIF2 inhibits GEF activity of EIF2B, an inhibition that requires the eIF2B1 subunit. Defects in eIF2B1 are a cause of leukoencephalopathy with vanishing white matter (VWM), a brain disease that is characterized by head trauma and motor deterioration. Recombinant human EIF2B1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Alternative Names :
Eukaryotic translation initiation factor 2B subunit alpha, Eukaryotic translation initiation factor 2B subunit 1 alpha 26kDa, EIF-2Balpha, EIF-2B, EIF2BA, EIF2Balpha, Translation initiation factor eIF-2B subunit alpha, eIF-2B GDP-GTP exchange factor subunit alpha
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Van der Knaap M.S. et al. (2002) Ann. Neurol 51: 264-270 ;; Mohammad-Qureshi S.S. et al. (2007) Mol. Cell. Biol. 27: 5225-5234.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Development
Molecular Weight :
35.8 kDa (325aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MDDKELIEYF KSQMKEDPDM ASAVAAIRTL LEFLKRDKGE TIQGLRANLT SAIETLCGVD SSVAVSSGGE LFLRFISLAS LEYSDYSKCK KIMIERGELF LRRISLSRNK IADLCHTFIK DGATILTHAY SRVVLRVLEA AVAAKKRFSV YVTESQPDLS GKKMAKALCH LNVPVTVVLD AAVGYIMEKA DLVIVGAEGV VENGGIINKI GTNQMAVCAK AQNKPFYVVA ESFKFVRLFP LNQQDVPDKF KYKADTLKVA QTGQDLKEEH PWVDYTAPSL ITLLFTDLGV LTPSAVSDEL IKLYL
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q14232
Internal Search Terms :
EIF2B1, Eukaryotic translation initiation factor 2B subunit 1 alpha 26kD, Eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kD, EIF-2B, EIF-2Balpha, EIF2B, EIF2BA, MGC117409, MGC125868, MGC125869,ATGP1024-10ug,ATGP1024-20ug,ATGP1024-50ug,ATGP1024-100ug,ATGP1024-250ug,ATGP1024-500ug,ATGP1024-1mg,ATGP1024-10,ATGP1024-20,ATGP1024-50,ATGP1024-100,ATGP1024-250,ATGP1024-500,ATGP1024-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.