product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human 17 beta-HSD8/HSD17B8 protein
catalog :
ATGP1001
quantity :
20 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human 17 beta-HSD8/HSD17B8 protein
Domain :
1-261aa
Catalog number (SKU) :
ATGP1001
NCBI :
NP_055049.1
Description :
HSD17B8, also known as estradiol 17-beta-dehydrogenase 8, belongs to the short-chain dehydrogenases/reductases (SDR) family. In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. It may play a role in biosynthesis of fatty acids in mitochondria. Recombinant human HSD17B8 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Alternative Names :
Hydroxysteroid 17-beta dehydrogenase 8,(3R)-3-hydroxyacyl-CoA dehydrogenase, FABGL, HKE6, RING2, SDR30C1, 17-beta-hydroxysteroid dehydrogenase 8, 17-beta-HSD 8, HSD17B8, 3-ketoacyl-[acyl-carrier-protein, reductase alpha subunit, KAR alpha subunit, 3-oxoacyl-[acyl-carrier-protein, reductase, Estradiol 17-beta-dehydrogenase 8, Protein Ke6, Ke6, Short chain dehydrogenase/reductase family 30C member 1, Testosterone 17-beta-dehydrogenase 8, H2-KE6
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 150mM NaCl
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Ando A., et al. (1996) Genomics. 35:600-602;; Rotinen M., et al. (2009) Endocrinol 200:85-92
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Metabolism
Molecular Weight :
29.1 kDa (281aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MASQLQNRLR SALALVTGAG SGIGRAVSVR LAGEGATVAA CDLDRAAAQE TVRLLGGPGS KEGPPRGNHA AFQADVSEAR AARCLLEQVQ ACFSRPPSVV VSCAGITQDE FLLHMSEDDW DKVIAVNLKG TFLVTQAAAQ ALVSNGCRGS IINISSIVGK VGNVGQTNYA ASKAGVIGLT QTAARELGRH GIRCNSVLPG FIATPMTQKV PQKVVDKITE MIPMGHLGDP EDVADVVAFL ASEDSGYITG TSVEVTGGLF M
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q92506
Internal Search Terms :
HSD17B8,ATGP1001-10ug,ATGP1001-20ug,ATGP1001-50ug,ATGP1001-100ug,ATGP1001-250ug,ATGP1001-500ug,ATGP1001-1mg,ATGP1001-10,ATGP1001-20,ATGP1001-50,ATGP1001-100,ATGP1001-250,ATGP1001-500,ATGP1001-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.