Recombinant human CMPK1 protein | NKMAX ATGP0982 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CMPK1 protein

catalog :

ATGP0982

quantity :

20 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CMPK1 protein

Domain :

1-228aa

Catalog number (SKU) :

ATGP0982

NCBI :

NP_057392.1

Description :

CMPK1, also known as uMP-CMP kinase and deoxycytidylate kinase, is an enzyme that catalyzes the phosphoryl transfer from ATP to uMP, CMP and dCMP. This enzymatic reaction leads to the formation of ADP and the corresponding nucleoside diphosphate, which are required for cellular nucleic acid synthesis. It also plays an important role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. Recombinant human CMPK1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Alternative Names :

uMP-CMP kinase, CMK, CMPK, RP11-511I2.1, uMK, uMP-CMPK, uMPK

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT, 100mM NaCl

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Van Rompay A.R., et al. (2000), Pharmacol. Ther. 87: 189-198.;; Liou J.Y., et al. (2002). Cancer Res. 62: 1624-1631.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Enzymes & Proteases

Molecular Weight :

28.0 kDa (248aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MLSRCRSGLL HVLGLSFLLQ TRRPILLCSP RLMKPLVVFV LGGPGAGKGT QCARIVEKYG YTHLSAGELL RDERKNPDSQ YGELIEKYIK EGKIVPVEIT ISLLKREMDQ TMAANAQKNK FLIDGFPRNQ DNLQGWNKTM DGKADVSFVL FFDCNNEICI ERCLERGKSS GRSDDNRESL EKRIQTYLQS TKPIIDLYEE MGKVKKIDAS KSVDEVFDEV VQIFDKEG

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P30085

Internal Search Terms :

CMPK1, uMP-CMP kinase, CMK, CMPK, RP11-511I2.1, uMK, uMP-CMPK, uMPK,ATGP0982-10ug,ATGP0982-20ug,ATGP0982-50ug,ATGP0982-100ug,ATGP0982-250ug,ATGP0982-500ug,ATGP0982-1mg,ATGP0982-10,ATGP0982-20,ATGP0982-50,ATGP0982-100,ATGP0982-250,ATGP0982-500,ATGP0982-1

more info or order :

NKMAX product webpage