product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human MTHFS protein
catalog :
ATGP0976
quantity :
20 ug
price :
80 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant human MTHFS protein
Domain :
1-203aa
Catalog number (SKU) :
ATGP0976
NCBI :
NP_006432
Description :
MTHFS, also known as 5-formyltetrahydrofolate cyclo-ligase, is a cytosolic protein involved in the formate metabolic process. MTHFS, with a magnesium cofactor, catalyzes the ATP-dependent reaction that reduces 5-formyltetrahydrofolate (5-MTHF) to 5, 10-methenyltetrahydrofolate (MTHF). MTHF is the substrate used by MTHFR (methylenetetrahydrofolate reductase) to generate 5-MTHF. MTHF is also a coenzyme used in thymidine biosynthesis by thymidylate synthase (FAD). Recombinant human MTHFS protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
5-formyltetrahydrofolate cyclo-ligase, Methenyl-THF synthetase
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 30% glycerol, 0.2M NaCl
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Field, M.S., et al. (2006) J. Biol. Chem. 281: 4215-4221.;; Lim, u., et al. (2007) Blood 109: 3050-3059.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Metabolism
Molecular Weight :
25.4 kDa (223aa) confirmed by MALDI-TOF
Amino Acid Sequence :
AAAAVSSAK RSLRGELKQR LRAMSAEERL RQSRVLSQKV IAHSEYQKSK RISIFLSMQD EIETEEIIKD IFQRGKICFI PRYRFQSNHM DMVRIESPEE ISLLPKTSWN IPQPGEGDVR EEALSTGGLD LIFMPGLGFD KHGNRLGRGK GYYDAYLKRC LQHQEVKPYT LALAFKEQIC LQVPVNENDM KVDEVLYEDS STA
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P49914
Internal Search Terms :
MTHFS, 5-formyltetrahydrofolate cyclo-ligase, Methenyl-THF synthetase,ATGP0976-10ug,ATGP0976-20ug,ATGP0976-50ug,ATGP0976-100ug,ATGP0976-250ug,ATGP0976-500ug,ATGP0976-1mg,ATGP0976-10,ATGP0976-20,ATGP0976-50,ATGP0976-100,ATGP0976-250,ATGP0976-500,ATGP0976-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.