Recombinant human TFAM protein | NKMAX ATGP0897 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human TFAM protein

catalog :

ATGP0897

quantity :

10 ug

price :

192 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human TFAM protein

Domain :

43-246aa

Catalog number (SKU) :

ATGP0897

NCBI :

NP_003192.1

Description :

TFAM, also known as MtTF1 or mtTFA, is a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. TFAM is located primarily in the nuclei of elongated spermatids and may be involved in the regulation of gene expression of the haploid male genome. TFAM has been associated with mitochondrial disorder in humans characterized by ocular myopathy, exercise intolerance and muscle wasting. Recombinant human TFAM protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Transcription factor A mitochondrial precursor, Transcription factor A, mitochondrial precursor, MtTF1, mtTFA, TCF6, TCF6L1, TCF6L2, TCF6L3

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Sinha RA., et al. (2010) Biochem Biophys Res Commun. 397(3):548-52.;; Aquilano K., et al. (2010) J Biol Chem. 285(28):21590-9.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

26.6 kDa (225aa) confirmed by MALDI-TOF

Amino Acid Sequence :

SSVLASCPK KPVSSYLRFS KEQLPIFKAQ NPDAKTTELI RRIAQRWREL PDSKKKIYQD AYRAEWQVYK EEISRFKEQL TPSQIMSLEK EIMDKHLKRK AMTKKKELTL LGKPKRPRSA YNVYVAERFQ EAKGDSPQEK LKTVKENWKN LSDSEKELYI QHAKEDETRY HNEMKSWEEQ MIEVGRKDLL RRTIKKQRKY GAEEC

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q00059

Internal Search Terms :

TFAM, Transcription factor A mitochondrial precursor, Transcription factor A, mitochondrial precursor, MtTF1, mtTFA, TCF6, TCF6L1, TCF6L2, TCF6L3,ATGP0897-10ug,ATGP0897-20ug,ATGP0897-50ug,ATGP0897-100ug,ATGP0897-250ug,ATGP0897-500ug,ATGP0897-1mg,ATGP0897-10,ATGP0897-20,ATGP0897-50,ATGP0897-100,ATGP0897-250,ATGP0897-500,ATGP0897-1

more info or order :

NKMAX product webpage