Recombinant human DDIT4 protein | NKMAX ATGP0896 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human DDIT4 protein

catalog :

ATGP0896

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human DDIT4 protein

Domain :

1-232aa

Catalog number (SKU) :

ATGP0896

NCBI :

NP_061931

Description :

DDIT4, also known as Dig2 or REDD1, is thought to have function in the regulation of reactive oxygen species. In response to stress due to DNA damage and glucocorticoid treatment, DDIT4 is upregulated at the transcriptional level. DDIT4 negatively regulates the mammalian target of Rapamycin, a serine/threonine kinase often referred to as mTOR. It is crucial in the coupling of extra- and intracellular cues to mTOR regulation. Recombinant human DDIT4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

DNA damage-inducible transcript 4 protein, Dig2, FLJ20500, REDD1, RP11-442H21.1, RTP801

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 5mM DTT, 1mM EDTA, 30% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Yoshida T., et al. (2010) Nat Med. 16(7):767-73.;; Regazzetti C., et al. (2010) J Biol Chem. 285(8):5157-64.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

27.5 kDa (252aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MPSLWDRFSS SSTSSSPSSL PRTPTPDRPP RSAWGSATRE EGFDRSTSLE SSDCESLDSS NSGFGPEEDT AYLDGVSLPD FELLSDPEDE HLCANLMQLL QESLAQARLG SRRPARLLMP SQLVSQVGKE LLRLAYSEPC GLRGALLDVC VEQGKSCHSV GQLALDPSLV PTFQLTLVLR LDSRLWPKIQ GLFSSANSPF LPGFSQSLTL STGFRVIKKK LYSSEQLLIE EC

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9NX09

Internal Search Terms :

DDIT4, DNA damage-inducible transcript 4 protein, Dig2, FLJ20500, REDD1, RP11-442H21.1, RTP801,ATGP0896-10ug,ATGP0896-20ug,ATGP0896-50ug,ATGP0896-100ug,ATGP0896-250ug,ATGP0896-500ug,ATGP0896-1mg,ATGP0896-10,ATGP0896-20,ATGP0896-50,ATGP0896-100,ATGP0896-250,ATGP0896-500,ATGP0896-1

more info or order :

NKMAX product webpage