Recombinant human METTL1 protein | NKMAX ATGP0869 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human METTL1 protein

catalog :

ATGP0869

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human METTL1 protein

Domain :

1-276aa

Catalog number (SKU) :

ATGP0869

NCBI :

NP_005362

Description :

METTL1 is known as tRNA (guanine-N (7) -) -methyltransferase which belongs to the methyltransferase superfamily. METTL1 shows high sequence similarity to yeast ORF YDL201w and has been shown to be inactivated by phosphorylation. This protein contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphylation. It catalyzes the formation of N (7) -methylguanine at position 46 (m7G46) in tRNA. Recombinant human METTL1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Methyltransferase like 1, TRM8, YDL201w

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 50mM NaCl

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Matsumoto K., et al. (2008) J. Biotechnol. 133: 453-460.;; Alexandrov A., et al. (2002) RNA 8:1253-1266;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Enzymes & Proteases

Molecular Weight :

33.6 kDa (296aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MAAETRNVAG AEAPPPQKRY YRQRAHSNPM ADHTLRYPVK PEEMDWSELY PEFFAPLTQN QSHDDPKDKK EKRAQAQVEF ADIGCGYGGL LVELSPLFPD TLILGLEIRV KVSDYVQDRI RALRAAPAGG FQNIACLRSN AMKHLPNFFY KGQLTKMFFL FPDPHFKRTK HKWRIISPTL LAEYAYVLRV GGLVYTITDV LELHDWMCTH FEEHPLFERV PLEDLSEDPV VGHLGTSTEE GKKVLRNGGK NFPAIFRRIQ DPVLQAVTSQ TSLPGH

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9UBP6

Internal Search Terms :

METTL1, Methyltransferase like 1, TRM8, YDL201w,ATGP0869-10ug,ATGP0869-20ug,ATGP0869-50ug,ATGP0869-100ug,ATGP0869-250ug,ATGP0869-500ug,ATGP0869-1mg,ATGP0869-10,ATGP0869-20,ATGP0869-50,ATGP0869-100,ATGP0869-250,ATGP0869-500,ATGP0869-1

more info or order :

NKMAX product webpage