Recombinant human WHSC2/NELFA protein | NKMAX ATGP0856 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human WHSC2/NELFA protein

catalog :

ATGP0856

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human WHSC2/NELFA protein

Domain :

1-539aa

Catalog number (SKU) :

ATGP0856

NCBI :

NP_005654

Description :

WHSC2, also known as NELF-A, is a protein factor required for DRB-sensitive transcription. This protein is one of the five components of the multisubunit NELF complex that cooperates with DSIF to repress RNA polymerase II elongation. Wolf-Hirschhorn syndrome is a multiple malformation syndrome characterized by mental and developmental defects resulting from a hemizygous deletion of the distal short arm of chromosome 4 (4p16. 3). Recombinant human WHSC2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Wolf-Hirschhorn syndrome candidate 2, NELF-A, NELFA, P/OKcl.15, Negative elongation factor A

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 5mM DTT, 1mM EDTA, 20% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Care A., et al. (2007) Nat Med. 13(5):613-8.;; Mariotti M., et al. (2000) FEBS Lett. 487(2):166-70.;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

60.6 kDa (559aa)

Amino Acid Sequence :

MPGQRRALSP KMASMRESDT GLWLHNKLGA TDELWAPPSI ASLLTAAVID NIRLCFHGLS SAVKLKLLLG TLHLPRRTVD EMKGALMEII QLASLDSDPW VLMVADILKS FPDTGSLNLE LEEQNPNVQD ILGELREKVG ECEASAMLPL ECQYLNKNAL TTLAGPLTPP VKHFQLKRKP KSATLRAELL QKSTETAQQL KRSAGVPFHA KGRGLLRKMD TTTPLKGIPK QAPFRSPTAP SVFSPTGNRT PIPPSRTLLR KERGVKLLDI SELDMVGAGR EAKRRRKTLD AEVVEKPAKE ETVVENATPD YAAGLVSTQK LGSLNNEPAL PSTSYLPSTP SVVPASSYIP SSETPPAPSS REASRPPEEP SAPSPTLPAQ FKQRAPMYNS GLSPATPTPA APTSPLTPTT PPAVAPTTQT PPVAMVAPQT QAPAQQQPKK NLSLTREQMF AAQEMFKTAN KVTRPEKALI LGFMAGSREN PCQEQGDVIQ IKLSEHTEDL PKADGQGSTT MLVDTVFEMN YATGQWTRFK KYKPMTNVS

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9H3P2

Internal Search Terms :

WHSC2, Wolf-Hirschhorn syndrome candidate 2, NELF-A, NELFA, P/OKcl.15, Negative elongation factor A,ATGP0856-10ug,ATGP0856-20ug,ATGP0856-50ug,ATGP0856-100ug,ATGP0856-250ug,ATGP0856-500ug,ATGP0856-1mg,ATGP0856-10,ATGP0856-20,ATGP0856-50,ATGP0856-100,ATGP0856-250,ATGP0856-500,ATGP0856-1

more info or order :

NKMAX product webpage