product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human 17 beta-HSD11/HSD17B11 protein
catalog :
ATGP0848
quantity :
20 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human 17 beta-HSD11/HSD17B11 protein
Domain :
20-285aa
Catalog number (SKU) :
ATGP0848
NCBI :
NP_057329
Description :
HSD17B11, also known as DHRS8 (dehydrogenase/reductase SDR family member 8), belongs to the HSD17B family of proteins, which regulate the availability of steroids within various tissues throughout the body. It is widely expressed with highest levels found in retina, pancreas, kidney, liver, lung, adrenal, small intestine, ovary and heart as well as in steroidogenic cells. This protein converts androstan-3-alpha, 17-beta-diol (3-alpha-diol) to androsterone, suggesting it may participate in androgen metabolism during steroidogenesis. Recombinant human HSD17B11 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Hydroxysteroid 17-beta dehydrogenase 11, Estradiol 17-beta-dehydrogenase 11, DHRS8, PAN1B, SDR16C2, 17-beta-hydroxysteroid dehydrogenase 11. 17-beta-HSD 11, 17bHSD11, 17betaHSD11, 17-beta-hydroxysteroid dehydrogenase XI, 17-beta-HSD XI, 17betaHSDXI, Cutaneous T-cell lymphoma-associated antigen HD-CL-03, CTCL-associated antigen HD-CL-03, Dehydrogenase/reductase SDR family member 8, Retinal short-chain dehydrogenase/reductase 2, retSDR2, Short chain dehydrogenase/reductase family 16C member 2
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Rotinen M., et al. (2010) J Steroid Biochem Mol Biol. 122(4):164-71.;; Nakamura Y., et al. (2009) Neoplasma. 56(4):317-20.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Enzymes & Proteases
Molecular Weight :
31.4 kDa (287aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MESFVKLFIP KRRKSVTGEI VLITGAGHGI GRLTAYEFAK LKSKLVLWDI NKHGLEETAA KCKGLGAKVH TFVVDCSNRE DIYSSAKKVK AEIGDVSILV NNAGVVYTSD LFATQDPQIE KTFEVNVLAH FWTTKAFLPA MTKNNHGHIV TVASAAGHVS VPFLLAYCSS KFAAVGFHKT LTDELAALQI TGVKTTCLCP NFVNTGFIKN PSTSLGPTLE PEEVVNRLMH GILTEQKMIF IPSSIAFLTT LERILPERFL AVLKQKI
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q8NBQ5
Internal Search Terms :
17 beta HSD 11, 17 beta HSD XI, 17 beta hydroxysteroid dehydrogenase 11, 17 beta hydroxysteroid dehydrogenase XI, 17-beta-HSD 11, 17-beta-HSD XI, 17betaHSD11, 17betaHSDXI, 17-beta-hydroxysteroid dehydrogenase 11. 17-beta-HSD 11, 17-beta-hydroxysteroid dehydrogenase XI, 17BHSD11, CTCL associated antigen HD CL 03, CTCL associated antigen HD-CL-03, CTCL-associated antigen HD-CL-03, Cutaneous T cell lymphoma-associated antigen HD CL 03, Cutaneous T cell lymphoma-associated antigen HD-CL-03, Cutaneous T-cell lymphoma-associated antigen HD CL 03, Cutaneous T-cell lymphoma-associated antigen HD-CL-03, Dehydrogenase/reductase SDR family member 8, DHRS8, Estradiol 17 beta dehydrogenase 11, Estradiol 17-beta-dehydrogenase 11, HSD17B11, Hydroxysteroid (17-beta) dehydrogenase 11, Hydroxysteroid 17 beta dehydrogenase 11, Hydroxysteroid 17-beta dehydrogenase 11, PAN1B, Retinal short chain dehydrogenase/reductase 2, Retinal short-chain dehydrogenase/reductase 2, RETSDR2, SDR16C2, Short chain dehydrog
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.