product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human PTRH2 protein
catalog :
ATGP0830
quantity :
20 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human PTRH2 protein
Domain :
64-179aa
Catalog number (SKU) :
ATGP0830
NCBI :
NP_057161
Description :
PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1, is a mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondria to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. The natural substrate for PTRH2 may be petidyl-tRNAs which drop off the ribosome during protein synthesis. Recombinant human PTRH2 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Peptidyl-tRNA hydrolase 2, BIT1, PTH2, CGI-147, Bcl-2 inhibitor of transcription 1
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Jan Y., et al. (2004) Cell. 116(5):751-62.;; De Pereda JM., et al. (2004) J Biol Chem. 279(9):8111-5.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Apoptosis
Molecular Weight :
14.9 kDa (137aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MEYKMILVVR NDLKMGKGKV AAQCSHAAVS AYKQIQRRNP EMLKQWEYCG QPKVVVKAPD EETLIALLAH AKMLGLTVSL IQDAGRTQIA PGSQTVLGIG PGPADLIDKV TGHLKLY
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q9Y3E5
Internal Search Terms :
PTRH2, Peptidyl-tRNA hydrolase 2, BIT1, PTH2, CGI-147, Bcl-2 inhibitor of transcription 1,ATGP0830-10ug,ATGP0830-20ug,ATGP0830-50ug,ATGP0830-100ug,ATGP0830-250ug,ATGP0830-500ug,ATGP0830-1mg,ATGP0830-10,ATGP0830-20,ATGP0830-50,ATGP0830-100,ATGP0830-250,ATGP0830-500,ATGP0830-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.