protein

Recombinant human SDCBP protein

ATGP0809

20 ug

80 USD

Recombinant human SDCBP protein

1-298aa

ATGP0809

NP_005616

SDCBP, also known as Syntenin1, is a multifunctional intracellular adapter protein. This protein contains tandemly repeated PDZ domains that react with the FYA (phe-tyr-ala) carboxyterminal amino acid sequence of the syndecans. It is involved in organization of protein complexes in the plasma membranes, regulation of B-cell development, activation of transcription factors, intracellular trafficking and cell-surface targeting, synaptic transmission, and axonal outgrowth. Recombinant human SDCBP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Syntenin-1, MDA-9, ST1, SYCL, TACIP18

0.5mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 40% glycerol

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Lee CH., et al. (2010) Comp Biochem Physiol C Toxicol Pharmacol. 152(2):195-201.;; Fisher PB., et al (2008) Cancer Res. 68(9):3087-93.

> 90% by SDS-PAGE

SDS-PAGE

Human

Neuroscience

34.6 kDa (318aa) confirmed by MALDI-TOF

< 1 EU per 1ug of protein (determined by LAL method)

MSLYPSLEDL KVDKVIQAQT AFSANPANPA ILSEASAPIP HDGNLYPRLY PELSQYMGLS LNEEEIRANV AVVSGAPLQG QLVARPSSIN YMVAPVTGND VGIRRAEIKQ GIREVILCKD QDGKIGLRLK SIDNGIFVQL VQANSPASLV GLRFGDQVLQ INGENCAGWS SDKAHKVLKQ AFGEKITMTI RDRPFERTIT MHKDSTGHVG FIFKNGKITS IVKDSSAARN GLLTEHNICE INGQNVIGLK DSQIADILST SGTVVTITIM PAFIFEHIIK RMAPSIMKSL MDHTIPEV

His-Tag

E.coli

Recombinant Protein

O00560

SDCBP, Syntenin-1, MDA-9, ST1, SYCL, TACIP18,ATGP0809-10ug,ATGP0809-20ug,ATGP0809-50ug,ATGP0809-100ug,ATGP0809-250ug,ATGP0809-500ug,ATGP0809-1mg,ATGP0809-10,ATGP0809-20,ATGP0809-50,ATGP0809-100,ATGP0809-250,ATGP0809-500,ATGP0809-1

Meyer A, et al, Metabolic reprogramming by Syntenin-1 directs RA FLS and endothelial cell-mediated inflammation and angiogenesis. (Cell Mol Immunol. 2024){https://pubmed.ncbi.nlm.nih.gov/38105293/}