Recombinant human SMNDC1 protein | NKMAX ATGP0807 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human SMNDC1 protein

catalog :

ATGP0807

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human SMNDC1 protein

Domain :

1-238aa

Catalog number (SKU) :

ATGP0807

NCBI :

NP_005862

Description :

SMNDC1 (survival motor neuron domain containing 1) is an essential splicing factor required for spliceosome assembly that belongs to the SMN family. It contains one Tudor domain with significant similarity to SMN (Survival Motor Neuron) and is expressed in skeletal muscle, pancreas and heart, localizing to Cajal bodies and nuclear speckles. Mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. Recombinant human SMNDC1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Survival of motor neuron-related-splicing factor 30, Survival of motor neuron-related-splicing factor 30

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 100mM NaCl

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Meister G., et al. (2001) EMBO J. 20:2304-2314;; Talbot K., et al. (1998) Hum. Mol. Genet. 7:2149-2156

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Apoptosis

Molecular Weight :

28.9 kDa (258aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MSEDLAKQLA SYKAQLQQVE AALSGNGENE DLLKLKKDLQ EVIELTKDLL STQPSETLAS SDSFASTQPT HSWKVGDKCM AVWSEDGQCY EAEIEEIDEE NGTAAITFAG YGNAEVTPLL NLKPVEEGRK AKEDSGNKPM SKKEMIAQQR EYKKKKALKK AQRIKELEQE REDQKVKWQQ FNNRAYSKNK KGQVKRSIFA SPESVTGKVG VGTCGIADKP MTQYQDTSKY NVRHLMPQ

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O75940

Internal Search Terms :

SMNDC1, Survival of motor neuron-related-splicing factor 30, Survival of motor neuron-related-splicing factor 30,ATGP0807-10ug,ATGP0807-20ug,ATGP0807-50ug,ATGP0807-100ug,ATGP0807-250ug,ATGP0807-500ug,ATGP0807-1mg,ATGP0807-10,ATGP0807-20,ATGP0807-50,ATGP0807-100,ATGP0807-250,ATGP0807-500,ATGP0807-1

more info or order :

NKMAX product webpage