Recombinant human RPA2 protein | NKMAX ATGP0792 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human RPA2 protein

catalog :

ATGP0792

quantity :

10 ug

price :

120 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human RPA2 protein

Domain :

1-270aa

Catalog number (SKU) :

ATGP0792

NCBI :

NP_002937

Description :

Replication Protein A (RPA) is a single stranded DNA binding protein. Human RPA is a heterotrimeric protein containing subunits of 14, 32 and 70kDa. This protein complex is highly conserved in eukaryotes and is essential in DNA replication, homologous recombination and nucleotide excision repair. The C-terminus of RPA2 can specfically intereact with the DNA repair enzyme uNG2 and repair factors XPA and Rad52, each of which functions in a different repair pathway. In addition, this protein binds specifically to the SH2 domain of Stat3 in vivo, and overexpression of RPA2 corresponds to the augmented growth factor-stimulated tyrosine phosphorylation and transcription activities of Stat3. Recombinant human RPA2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Replication protein A 32 kDa subunit, Replication protein A 32 kDa subunit, REPA2, RPA32, RPA32, RP-A p32, RP-A p34

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 2mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Wang M., et al. (2000) Biochemistry. 39(21):6433-9. ;; Mer G., et al. (2000) Cell. 103(3):449-56.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

31.7 kDa (293aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MWNSGFE SYGSSSYGGA GGYTQSPGGF GSPAPSQAEK KSRARAQHIV PCTISQLLSA TLVDEVFRIG NVEISQVTIV GIIRHAEKAP TNIVYKIDDM TAAPMDVRQW VDTDDTSSEN TVVPPETYVK VAGHLRSFQN KKSLVAFKIM PLEDMNEFTT HILEVINAHM VLSKANSQPS AGRAPISNPG MSEAGNFGGN SFMPANGLTV AQNQVLNLIK ACPRPEGLNF QDLKNQLKHM SVSSIKQAVD FLSNEGHIYS TVDDDHFKST DAE

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P15927

Internal Search Terms :

RPA2,ATGP0792-10ug,ATGP0792-20ug,ATGP0792-50ug,ATGP0792-100ug,ATGP0792-250ug,ATGP0792-500ug,ATGP0792-1mg,ATGP0792-10,ATGP0792-20,ATGP0792-50,ATGP0792-100,ATGP0792-250,ATGP0792-500,ATGP0792-1

more info or order :

NKMAX product webpage