Recombinant human SH2D1A protein | NKMAX ATGP0783 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human SH2D1A protein

catalog :

ATGP0783

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human SH2D1A protein

Domain :

1-128aa

Catalog number (SKU) :

ATGP0783

NCBI :

NP_002342

Description :

SH2D1A is an inhibitor of the signaling lymphocyte activation molecule (SLAM) self-association. This protein is expressed at a high level in thymus and lung, with a lower level of expression in spleen and liver. Defects in SH2D1A are a cause of X-linked lymphoproliferative disease (XLPD) also known as Duncan disease. XLPD is characterized by a rare congenital immunodeficiency following Epstein-Barr virus (EBV) infection. Recombinant human SH2D1A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Alternative Names :

SH2 domain-containing protein 1A, DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4)

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Schwartzberg PL., et al. (2010) Immunity. 32(2):253-65.;; Lenardo MJ., et al (2009) J Clin Invest. 119(10):2976-89;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

16.3 kDa (148aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MDAVAVYHGK ISRETGEKLL LATGLDGSYL LRDSESVPGV YCLCVLYHGY IYTYRVSQTE TGSWSAETAP GVHKRYFRKI KNLISAFQKP DQGIVIPLQY PVEKKSSARS TQGTTGIRED PDVCLKAP

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O60880

Internal Search Terms :

SH2D1A, SH2 domain-containing protein 1A, DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD,ATGP0783-10ug,ATGP0783-20ug,ATGP0783-50ug,ATGP0783-100ug,ATGP0783-250ug,ATGP0783-500ug,ATGP0783-1mg,ATGP0783-10,ATGP0783-20,ATGP0783-50,ATGP0783-100,ATGP0783-250,ATGP0783-500,ATGP0783-1

more info or order :

NKMAX product webpage