Recombinant human RhoGDI 1/ARHGDIA protein | NKMAX ATGP0775 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human RhoGDI 1/ARHGDIA protein

catalog :

ATGP0775

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human RhoGDI 1/ARHGDIA protein

Domain :

24-204aa

Catalog number (SKU) :

ATGP0775

NCBI :

NP_004300

Description :

Rho GDP-dissociation inhibitor 1, also known ARHGDIA, belong to the RAS gene superfamily encoding small guanine nucleotide exchange (GTP/GDP) factors. Localized to the cytoplasm, ARHGDIA inhibits the dissociation of GDP from Rho proteins, thereby preventing GTP from binding to and subsequently activating Rho proteins. In humans ARHGDIA can be phosphorylated at Ser 101 by p21-activated kinase, an event that inhibits ARHGDIA activity and may result in positive feedback regulation of certain ARHGDIA target proteins. Recombinant human ARHGDIA protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Rho GDP-dissociation inhibitor 1, GDIA1, RHOGDI, RHOGDI-1, Rho-GDI alpha

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

DerMardirossian C., et al. (2006) Mol Biol Cell. 17:4760-4768.;; Leffers H., et al. (1993) Exp Cell Res. 209:165-174.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

22.9 kDa (202aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MSVNYKPPAQ KSIQEIQELD KDDESLRKYK EALLGRVAVS ADPNVPNVVV TGLTLVCSSA PGPLELDLTG DLESFKKQSF VLKEGVEYRI KISFRVNREI VSGMKYIQHT YRKGVKIDKT DYMVGSYGPR AEEYEFLTPV EEAPKGMLAR GSYSIKSRFT DDDKTDHLSW EWNLTIKKDW KD

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P52565

Internal Search Terms :

ARHGDIA, Rho GDP-dissociation inhibitor 1, GDIA1, RHOGDI, RHOGDI-1, Rho-GDI alpha,ATGP0775-10ug,ATGP0775-20ug,ATGP0775-50ug,ATGP0775-100ug,ATGP0775-250ug,ATGP0775-500ug,ATGP0775-1mg,ATGP0775-10,ATGP0775-20,ATGP0775-50,ATGP0775-100,ATGP0775-250,ATGP0775-500,ATGP0775-1

more info or order :

NKMAX product webpage