Recombinant human Crk protein | NKMAX ATGP0766 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Crk protein

catalog :

ATGP0766

quantity :

10 ug

price :

240 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Crk protein

Domain :

1-204aa

Catalog number (SKU) :

ATGP0766

NCBI :

NP_005197

Description :

CRK is a member of signaling adapter protein family that binds to several tyrosine-phosphorylated proteins. This protein is involved in many cellular processes including apoptosis, proliferation, and differentiation. It has a modular domain architecture consisting of an SH2 followed by two SH3 domains (src-homology domains). The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Recombinant human CRK protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Alternative Names :

Adapter molecule crk, Proto-oncogene c-Crk, p38, CRKII

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Muir TW., et al (2006) Biochemistry. 45(29):8874-84.;; Inagaki F., et al. (2007) Nat Struct Mol Biol. 14(6):503-10.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

25.0 kDa (224aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MAGNFDSEER SSWYWGRLSR QEAVALLQGQ RHGVFLVRDS STSPGDYVLS VSENSRVSHY IINSSGPRPP VPPSPAQPPP GVSPSRLRIG DQEFDSLPAL LEFYKIHYLD TTTLIEPVSR SRQGSGVILR QEEAEYVRAL FDFNGNDEED LPFKKGDILR IRDKPEEQWW NAEDSEGKRG MIPVPYVEKY RPASASVSAL IGGR

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P46108

Internal Search Terms :

Crk, Adapter molecule crk, Proto-oncogene c-Crk, p38, CRKII,ATGP0766-10ug,ATGP0766-20ug,ATGP0766-50ug,ATGP0766-100ug,ATGP0766-250ug,ATGP0766-500ug,ATGP0766-1mg,ATGP0766-10,ATGP0766-20,ATGP0766-50,ATGP0766-100,ATGP0766-250,ATGP0766-500,ATGP0766-1

more info or order :

NKMAX product webpage