Recombinant human MAGEA3 protein | NKMAX ATGP0757 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human MAGEA3 protein

catalog :

ATGP0757

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human MAGEA3 protein

Domain :

1-314aa

Catalog number (SKU) :

ATGP0757

NCBI :

NP_005353.1

Description :

Melanoma-associated antigen 3, also known MAGEA3, is a member of the MAGE gene family, which comprises 12 known genes, of which 6 are expressed in tumors. The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGEA3 is a tumor-specific antigen widely expressed in solid and hematologic malignancies, but not in normal tissues, with the exception of testis and placenta. Therefore, MAGEA3 is an excellent candidate tumor antigen. Recombinant human MAGEA3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Melanoma-associated antigen 3, CT1.3, HIP8, HYPD, MAGE3, MZ2 D

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 100mM NaCl

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Roqner u C., et al. (1995) Genomics. 29(3):725-31.;; Jang S J., et al. (2001) Cancer Res. 61(21):7959-63.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

37.1 kDa (337aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

PLEQRS QHCKPEEGLE ARGEALGLVG AQAPATEEQE AASSSSTLVE VTLGEVPAAE SPDPPQSPQG ASSLPTTMNY PLWSQSYEDS SNQEEEGPST FPDLESEFQA ALSRKVAELV HFLLLKYRAR EPVTKAEMLG SVVGNWQYFF PVIFSKASSS LQLVFGIELM EVDPIGHLYI FATCLGLSYD GLLGDNQIMP KAGLLIIVLA IIAREGDCAP EEKIWEELSV LEVFEGREDS ILGDPKKLLT QHFVQENYLE YRQVPGSDPA CYEFLWGPRA LVETSYVKVL HHMVKISGGP HISYPPLHEW VLREGEE

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P43357

Internal Search Terms :

MAGEA3, Melanoma-associated antigen 3, CT1.3, HIP8, HYPD, MAGE3, MZ2 D,ATGP0757-10ug,ATGP0757-20ug,ATGP0757-50ug,ATGP0757-100ug,ATGP0757-250ug,ATGP0757-500ug,ATGP0757-1mg,ATGP0757-10,ATGP0757-20,ATGP0757-50,ATGP0757-100,ATGP0757-250,ATGP0757-500,ATGP0757-1

more info or order :

NKMAX product webpage