Recombinant human PIN/DYNLL1 protein | NKMAX ATGP0744 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human PIN/DYNLL1 protein

catalog :

ATGP0744

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human PIN/DYNLL1 protein

Domain :

1-89aa

Catalog number (SKU) :

ATGP0744

NCBI :

NP_003737.1

Description :

DYNLL1, also known as DLC8 or PIN (protein inhibitor of neuronal nitric oxide synthase), has been identified as a protein that interacts with NOS1 resulting in NOS1 inhibition. Binding of this protein destabilizes NOS1 (Neuronal nitric oxide synthase) dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. DYNLL1 is a ubiquitously expressed protein that exhibits high expression in testis and moderate expression in brain. Recombinant human DYNLL1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Dynein light chain 1 cytoplasmic, DLC1, DLC8, DNCL1, DNCLC1, hdlc1, LC8, LC8a, MGC126137, MGC126138, PIN, 8 kDa dynein light chain, Dynein light chain LC8-type 1, Protein inhibitor of neuronal nitric oxide synthase

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 1mM DTT, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Nakano H., et al. (2010) J Biol Chem. 285(14):10841-9.;; Kubota T., et al. (2009) J Virol. 83(13):6952-6.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

12.5 kDa (109aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MCDRKAVIKN ADMSEEMQQD SVECATQALE KYNIEKDIAA HIKKEFDKKY NPTWHCIVGR NFGSYVTHET KHFIYFYLGQ VAILLFKSG

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P63167

Internal Search Terms :

PIN, DYNLL1, Dynein light chain 1 cytoplasmic, DLC1, DLC8, DNCL1, DNCLC1, hdlc1, LC8, LC8a, MGC126137, MGC126138, PIN,ATGP0744-10ug,ATGP0744-20ug,ATGP0744-50ug,ATGP0744-100ug,ATGP0744-250ug,ATGP0744-500ug,ATGP0744-1mg,ATGP0744-10,ATGP0744-20,ATGP0744-50,ATGP0744-100,ATGP0744-250,ATGP0744-500,ATGP0744-1

more info or order :

NKMAX product webpage