Recombinant human DIRAS1 protein | NKMAX ATGP0724 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human DIRAS1 protein

catalog :

ATGP0724

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human DIRAS1 protein

Domain :

1-195aa

Catalog number (SKU) :

ATGP0724

NCBI :

NP_660156.1

Description :

DIRAS1 belongs to a distinct branch of the functionally diverse Ras superfamily of monomeric GTPases. Ras proteins function as binary molecular switches that control intracellular signaling networks. Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. Ras and ras-related proteins are often deregulated in cancers, leading to increased invasion and metastasis, and decreased apoptosis. DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form. Recombinant human DIRAS1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

GTP-binding protein Di-Ras1., Di-Ras1, FLJ42681, GBTS1, RIG, GTP-binding protein Di-Ras1.

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT, 0.1M NaCl, 1mM EDTA

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Ellis CA., et al. (2002) Proc Natl Acad Sci u S A. 99(15):9876-81. ;; Kontani K., et al. (2002) J Biol Chem. 277(43):41070-8.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

24.1 kDa (215aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MPEQSNDYRV VVFGAGGVGK SSLVLRFVKG TFRDTYIPTI EDTYRQVISC DKSVCTLQIT DTTGSHQFPA MQRLSISKGH AFILVFSVTS KQSLEELGPI YKLIVQIKGS VEDIPVMLVG NKCDETQREV DTREAQAVAQ EWKCAFMETS AKMNYNVKEL FQELLTLETR RNMSLNIDGK RSGKQKRTDR VKGKC

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O95057

Internal Search Terms :

DIRAS1, GTP-binding protein Di-Ras1., Di-Ras1, FLJ42681, GBTS1, RIG, GTP-binding protein Di-Ras1.,ATGP0724-10ug,ATGP0724-20ug,ATGP0724-50ug,ATGP0724-100ug,ATGP0724-250ug,ATGP0724-500ug,ATGP0724-1mg,ATGP0724-10,ATGP0724-20,ATGP0724-50,ATGP0724-100,ATGP0724-250,ATGP0724-500,ATGP0724-1

more info or order :

NKMAX product webpage