Recombinant human Guanylate kinase 1/GUK1 protein | NKMAX ATGP0690 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Guanylate kinase 1/GUK1 protein

catalog :

ATGP0690

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Guanylate kinase 1/GUK1 protein

Domain :

1-197aa

Catalog number (SKU) :

ATGP0690

NCBI :

NP_000849

Description :

GuK1, also known as GMK, belongs to the guanylate kinase family. This protein exists as a monomer that catalyzes the ATP-dependent conversion of GMP to GDP, thereby playing an essential role in the recycling of GMP. Via its catalytic activity, GuK1 is thought to participate in regulating the supply of guanine nucleotides to signal transduction pathways. Overexpression of GuK1 is associated with pituitary adenocarcinomas, suggesting that GuK1 is involved in tumorigenesis. Recombinant human GuK1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Guanylate kinase, GMK, GMP kinase, GMPK

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Da Rocha AA., et al. (2006) Pituitary. 9(2):83-92. ;; Brady WA., et al. (1996) J Biol Chem. 271(28):16734-40.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

23.9 kDa (217aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MSGPRPVVLS GPSGAGKSTL LKRLLQEHSG IFGFSVSHTT RNPRPGEENG KDYYFVTREV MQRDIAAGDF IEHAEFSGNL YGTSKVAVQA VQAMNRICVL DVDLQGVRNI KATDLRPIYI SVQPPSLHVL EQRLRQRNTE TEESLVKRLA AAQADMESSK EPGLFDVVII NDSLDQAYAE LKEALSEEIK KAQRTGA

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q16774

Internal Search Terms :

GUK-1, GUK1, GUK 1, Guanylate Kinase, GMPK, GMP kinase, GMK, ATGP0690-10ug, ATGP0690-20ug, ATGP0690-50ug, ATGP0690-100ug, ATGP0690-250ug, ATGP0690-500ug, ATGP0690-1mg, ATGP0690-010, ATGP0690-020, ATGP0690-050, ATGP0690-100, ATGP0690-250, ATGP0690-500, ATGP0690-01M

more info or order :

NKMAX product webpage