Recombinant human TPM1 protein | NKMAX ATGP0683 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human TPM1 protein

catalog :

ATGP0683

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human TPM1 protein

Domain :

1-284aa

Catalog number (SKU) :

ATGP0683

NCBI :

NP_000357.3

Description :

TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. TPM1 is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. Recombinant human TPM1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Tropomyosin alpha-1 chain, TPM1, CMD1Y, HTM-alpha, TMSA, Tropomyosin-1, Alpha-tropomyosin, Tropomyosin alpha-1 chain

Concentration :

0.25mg/ml (determined by BCA assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 0.2M NaCl,1mM EDTA, 0.1mM PMSF

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Lees-Miller JP. (1991) Bioessays. 13(9):429-37.;; Perry SV. (2001) J Muscle Res Cell Motil. 22(1):5-49.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cytoskeleton

Molecular Weight :

35.0 kDa (304aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher))

Amino Acid Sequence :

MDAIKKKMQM LKLDKENALD RAEQAEADKK AAEDRSKQLE DELVSLQKKL KGTEDELDKY SEALKDAQEK LELAEKKATD AEADVASLNR RIQLVEEELD RAQERLATAL QKLEEAEKAA DESERGMKVI ESRAQKDEEK MEIQEIQLKE AKHIAEDADR KYEEVARKLV IIESDLERAE ERAELSEGQV RQLEEQLRIM DQTLKALMAA EDKYSQKEDR YEEEIKVLSD KLKEAETRAE FAERSVTKLE KSIDDLEDEL YAQKLKYKAI SEELDHALND MTSM

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P09493

Internal Search Terms :

TPM1, Tropomyosin alpha-1 chain, TPM1, CMD1Y, HTM-alpha, TMSA, Tropomyosin-1, Alpha-tropomyosin, Tropomyosin alpha-1 chain,ATGP0683-10ug,ATGP0683-20ug,ATGP0683-50ug,ATGP0683-100ug,ATGP0683-250ug,ATGP0683-500ug,ATGP0683-1mg,ATGP0683-10,ATGP0683-20,ATGP0683-50,ATGP0683-100,ATGP0683-250,ATGP0683-500,ATGP0683-1

more info or order :

NKMAX product webpage