Recombinant human MMAB protein | NKMAX ATGP0677 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human MMAB protein

catalog :

ATGP0677

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human MMAB protein

Domain :

33-250aa

Catalog number (SKU) :

ATGP0677

NCBI :

AAH05054

Description :

MMAB is a protein that catalyzes the final step in the conversion of vitamin B (12) into adenosylcobalamin (AdoCbl), a vitamin B12 containing coenzyme for methylmalonyl-CoA mutase (MCM). Impaired MMAB activity leads to the inherited disorder vitamin B12 dependent methylmalonic aciduria linked to the cblB complementation group. Recombinant human MMAB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Alternative Names :

Methylmalonic aciduria (cobalamin deficiency) cblB type, ATR, ATP:cob(I)alamin adenosyltransferase, Methylmalonic aciduria (cobalamin deficiency) cblB type

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Gravel RA., et al. (2009) Mol Genet Metab. 98(3):278-84;; Edwards AM., et al (2004) J Biol Chem. 279(22):23646-53.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Enzymes & Proteases

Molecular Weight :

26.3 kDa (239aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MQSRGPQGVE DGDRPQPSSK TPRIPKIYTK TGDKGFSSTF TGERRPKDDQ VFEAVGTTDE LSSAIGFALE LVTEKGHTFA EELQKIQCTL QDVGSALATP CSSAREAHLK YTTFKAGPIL ELEQWIDKYT SQLPPLTAFI LPSGGKISSA LHFCRAVCRR AERRVVPLVQ MGETDANVAK FLNRLSDYLF TLARYAAMKE GNQEKIYKKN DPSAESEGL

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q96EY8

Internal Search Terms :

MMAB, Methylmalonic aciduria (cobalamin deficiency) cblB type, ATR, ATP:cob(I)alamin adenosyltransferase, Methylmalonic aciduria (cobalamin deficiency) cblB type,ATGP0677-10ug,ATGP0677-20ug,ATGP0677-50ug,ATGP0677-100ug,ATGP0677-250ug,ATGP0677-500ug,ATGP0677-1mg,ATGP0677-10,ATGP0677-20,ATGP0677-50,ATGP0677-100,ATGP0677-250,ATGP0677-500,ATGP0677-1

more info or order :

NKMAX product webpage