Recombinant human DR1 protein | NKMAX ATGP0669 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human DR1 protein

catalog :

ATGP0669

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human DR1 protein

Domain :

1-176aa

Catalog number (SKU) :

ATGP0669

NCBI :

NP_001929.1

Description :

DR1, also known as NC2-beta, is a TBP (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. By selectively repressing polymerases II and III, DR1 may shift the physiological balance of transcriptional output in favor of polymerase I. Recombinant human DR1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography

Alternative Names :

Down-regulator of transcription 1 TBP-binding, NC2, NC2-BETA, Down-regulator of transcription 1, TBP-binding

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 0.1mM PMSF ,10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

White RJ., et al. (2010) Nucleic Acids Res. 38(4):1228-39. ;; Collart MA., et al. (2008) Nucleic Acids Res. 36(2):539-49.;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

21.6 kDa (196aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MASSSGNDDD LTIPRAAINK MIKETLPNVR VANDARELVV NCCTEFIHLI SSEANEICNK SEKKTISPEH VIQALESLGF GSYISEVKEV LQECKTVALK RRKASSRLEN LGIPEEELLR QQQELFAKAR QQQAELAQQE WLQMQQAAQQ AQLAAASASA SNQAGSSQDE EDDDDI

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q01658

Internal Search Terms :

DR1, Down-regulator of transcription 1 TBP-binding, NC2, NC2-BETA, Down-regulator of transcription 1, TBP-binding,ATGP0669-10ug,ATGP0669-20ug,ATGP0669-50ug,ATGP0669-100ug,ATGP0669-250ug,ATGP0669-500ug,ATGP0669-1mg,ATGP0669-10,ATGP0669-20,ATGP0669-50,ATGP0669-100,ATGP0669-250,ATGP0669-500,ATGP0669-1

more info or order :

NKMAX product webpage