Recombinant human Tau 352 (0N3R)/MAPT protein | NKMAX ATGP0646 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Tau 352 (0N3R)/MAPT protein

catalog :

ATGP0646

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Tau 352 (0N3R)/MAPT protein

Domain :

1-352aa

Catalog number (SKU) :

ATGP0646

NCBI :

NP_058525

Description :

MAPT, also known as TAu, is a neuronal microtubule associated protein found predominantly on axons. The function of this protein is to promote tubulin polymerisation and stabilise microtubules, but it also serves to link certain signalling pathways to the cytoskeleton. MAPT, in its hyperphosphorylated form, is the major component of paired helical filaments (PHF) and neurofibrillary lesions in Alzheimer's disease (AD) brain. Recombinant human MAPT protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques

Alternative Names :

microtubule-associated protein isoform 4, fetal tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, G protein beta1/gamma2 subunit-interacting factor 1, protein phosphatase 1 regulatory subunit 103, MTBT1, PPND, FTDP-17, TAU, MSTD, MTBT2, FLJ31424, MGC138549, PPP1R103, tau-40, DDPAC, MAPTL

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M Nacl, 1mM DTT, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Jack CR Jr., et al. (2010) Lancet Neurol. 9(1):119-28.;; Buescher JL., et al. (2010) J Biol Chem. 285(11):7957-63.;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Neuroscience

Molecular Weight :

38.9 kDa (372aa) confirmed by MALDI-TOF (Real Molecular weight on SDS-PAGE will be shift up)

Amino Acid Sequence :

MAEPRQEFEV MEDHAGTYGL GDRKDQGGYT MHQDQEGDTD AGLKAEEAGI GDTPSLEDEA AGHVTQARMV SKSKDGTGSD DKKAKGADGK TKIATPRGAA PPGQKGQANA TRIPAKTPPA PKTPPSSGEP PKSGDRSGYS SPGSPGTPGS RSRTPSLPTP PTREPKKVAV VRTPPKSPSS AKSRLQTAPV PMPDLKNVKS KIGSTENLKH QPGGGKVQIV YKPVDLSKVT SKCGSLGNIH HKPGGGQVEV KSEKLDFKDR VQSKIGSLDN ITHVPGGGNK KIETHKLTFR ENAKAKTDHG AEIVYKSPVV SGDTSPRHLS NVSSTGSIDM VDSPQLATLA DEVSASLAKQ GL

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P10636

Internal Search Terms :

Tau, Microtubule-associated protein tau, TAu, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, Microtubule-associated protein tau,ATGP0646-10ug,ATGP0646-20ug,ATGP0646-50ug,ATGP0646-100ug,ATGP0646-250ug,ATGP0646-500ug,ATGP0646-1mg,ATGP0646-10,ATGP0646-20,ATGP0646-50,ATGP0646-100,ATGP0646-250,ATGP0646-500,ATGP0646-1

more info or order :

NKMAX product webpage