Recombinant human GALK1 protein | NKMAX ATGP0641 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human GALK1 protein

catalog :

ATGP0641

quantity :

20 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human GALK1 protein

Domain :

1-392aa

Catalog number (SKU) :

ATGP0641

NCBI :

NP_000145.1

Description :

GALK1, also often designated galactokinase, is important in the first step of the galactose metabolism pathway. (ATP + D-galactose = ADP + alpha-D-galactose 1-phosphate) Defects in GALK1 are the cause of galactosemia II. It is an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of galactitol in the lenses. Recombinant human GALK1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Galactokinase, GALK, GK1, Galactokinase

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol 0.1M NaCl, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Ai Y., et al. (1995) Biochem Biophys Res Commun. 212(2):687-91.;; Hunter M., et al. (2001) Hum Mutat. 17(1):77-8.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Enzymes & Proteases

Molecular Weight :

44.4 (412aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MAALRQPQVA ELLAEARRAF REEFGAEPEL AVSAPGRVNL IGEHTDYNQG LVLPMALELM TVLVGSPRKD GLVSLLTTSE GADEPQRLQF PLPTAQRSLE PGTPRWANYV KGVIQYYPAA PLPGFSAVVV SSVPLGGGLS SSASLEVATY TFLQQLCPDS GTIAARAQVC QQAEHSFAGM PCGIMDQFIS LMGQKGHALL IDCRSLETSL VPLSDPKLAV LITNSNVRHS LASSEYPVRR RQCEEVARAL GKESLREVQL EELEAARDLV SKEGFRRARH VVGEIRRTAQ AAAALRRGDY RAFGRLMVES HRSLRDDYEV SCPELDQLVE AALAVPGVYG SRMTGGGFGG CTVTLLEASA APHAMRHIQE HYGGTATFYL SQAADGAKVL CL

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P51570

Internal Search Terms :

GALK1, Galactokinase, GALK, GK1, Galactokinase,ATGP0641-10ug,ATGP0641-20ug,ATGP0641-50ug,ATGP0641-100ug,ATGP0641-250ug,ATGP0641-500ug,ATGP0641-1mg,ATGP0641-10,ATGP0641-20,ATGP0641-50,ATGP0641-100,ATGP0641-250,ATGP0641-500,ATGP0641-1

more info or order :

NKMAX product webpage