Recombinant human TIP30/HTATIP2 protein | NKMAX ATGP0631 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human TIP30/HTATIP2 protein

catalog :

ATGP0631

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human TIP30/HTATIP2 protein

Domain :

1-242aa

Catalog number (SKU) :

ATGP0631

NCBI :

AAH15358

Description :

HTATIP2, also known as TIP30, is a member of the short-chain dehydrogenases/reductases (SDR) family. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in This protein are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for HTATIP2 in antitumor therapy. Recombinant human HTATIP2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques

Alternative Names :

Oxidoreductase HTATP2, CC3, TIP30, SDR44u1, Oxidoreductase HTATP2, HTATIP 2, HTATIP-2, CC-3, TIP 30, TIP-30

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Shtivelman E., et al. (1997) Oncogene. 14(18):2167-73. ;; Xiao H., et al. (1998) Proc Natl Acad Sci u S A. 95(5):2146-2151.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

29.3 kDa (262aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MAETEALSKL REDFRMQNKS VFILGASGET GRVLLKEILE QGLFSKVTLI GRRKLTFDEE AYKNVNQEVV DFEKLDDYAS AFQGHDVGFC CLGTTRGKAG AEGFVRVDRD YVLKSAELAK AGGCKHFNLL SSKGADKSSN FLYLQVKGEV EAKVEELKFD RYSVFRPGVL LCDRQESRPG EWLVRKFFGS LPDSWARGHS VPVVTVVRAM LNNVVRPRDK QMELLENKAI HDLGKAHGSL KP

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9BUP3

Internal Search Terms :

TIP-30, TIP30, TIP 30, SDR44u1, Oxidoreductase HTATP2, HTATIP-2, HTATIP2, HTATIP 2, CC-3, CC3, CC 3, ATGP0631-10ug, ATGP0631-20ug, ATGP0631-50ug, ATGP0631-100ug, ATGP0631-250ug, ATGP0631-500ug, ATGP0631-1mg, ATGP0631-010, ATGP0631-020, ATGP0631-050, ATGP0631-100, ATGP0631-250, ATGP0631-500, ATGP0631-01M

more info or order :

NKMAX product webpage