Recombinant human beta 2-Microglobulin/B2M protein | NKMAX ATGP0624 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human beta 2-Microglobulin/B2M protein

catalog :

ATGP0624

quantity :

10 ug

price :

110 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human beta 2-Microglobulin/B2M protein

Domain :

21-119aa

Catalog number (SKU) :

ATGP0624

NCBI :

NP_004039.1

Description :

Beta2 microglobulin, also known as B2M, is a component of MHC class I molecules, Involved in the presentation of peptide antigens to the immune system. B2M is a protein found on the surface of many cells and plentiful on the surface of white blood cells. Increased production or destruction of these cells causes B2M levels in the blood to increase. This increase is seen in people with cancers involving white blood cells, but it is particularly meaningful in people newly diagnosed with multiple myeloma. Multiple myeloma is a malignancy (cancer) of a certain kind of white blood cell, called a plasma cell. B2M Testing is done primarily when evaluating a person for certain kinds of cancer affecting white blood cells including chronic lymphocytic leukemia, non-Hodgkin's lymphoma, and multiple myeloma or kidney disease. Recombinant B2M protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Beta-2-microglobulin, CDABP0092, HDCMA22P

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 2mM DTT, 100mM NaCl

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Huang WC., et al (2010) J Biol Chem. 285(11):7947-56;; Morabito A., et al. (2009) Hum Immunol. 70(7):492-5.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

14 kDa (120aa) confirmed by MALDI-TOF

Amino Acid Sequence :

IQRTPKIQV YSRHPAENGK SNFLNCYVSG FHPSDIEVDL LKNGERIEKV EHSDLSFSKD WSFYLLYYTE FTPTEKDEYA CRVNHVTLSQ PKIVKWDRDM

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P61769

Internal Search Terms :

b2-Microglobulin, B2M, Beta-2-microglobulin, CDABP0092, HDCMA22P,ATGP0624-10ug,ATGP0624-20ug,ATGP0624-50ug,ATGP0624-100ug,ATGP0624-250ug,ATGP0624-500ug,ATGP0624-1mg,ATGP0624-10,ATGP0624-20,ATGP0624-50,ATGP0624-100,ATGP0624-250,ATGP0624-500,ATGP0624-1

more info or order :

NKMAX product webpage