Recombinant human GCDH protein | NKMAX ATGP0622 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human GCDH protein

catalog :

ATGP0622

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human GCDH protein

Domain :

45-438aa

Catalog number (SKU) :

ATGP0622

NCBI :

NP_000150

Description :

Glutaryl-CoA dehydrogenase (GCDH) belongs to the acyl-CoA dehydrogenase family. GCDH catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO (2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. This Protein uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. Recombinant GCDH protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Glutaryl-CoA dehydrogenase, ACAD5, GCD, Glutaryl-CoA dehydrogenase, ACAD-5, ACAD 5,

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 5mM DTT, 200mM NaCl

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Keyser B., et al. (2008) Hum. Mol. Genet. 17:3854-3863;; Westover JB., et al. (2001) Biochemistry. 40(46):14106-14.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Metabolism

Molecular Weight :

45.7 kDa (415aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MRPEFDWQDP LVLEEQLTTD EILIRDTFRT YCQERLMPRI LLANRNEVFH REIISEMGEL GVLGPTIKGY GCAGVSSVAY GLLARELERV DSGYRSAMSV QSSLVMHPIY AYGSEEQRQK YLPQLAKGEL LGCFGLTEPN SGSDPSSMET RAHYNSSNKS YTLNGTKTWI TNSPMADLFV VWARCEDGCI RGFLLEKGMR GLSAPRIQGK FSLRASATGM IIMDGVEVPE ENVLPGASSL GGPFGCLNNA RYGIAWGVLG ASEFCLHTAR QYALDRMQFG VPLARNQLIQ KKLADMLTEI TLGLHACLQL GRLKDQDKAA PEMVSLLKRN NCGKALDIAR QARDMLGGNG ISDEYHVIRH AMNLEAVNTY EGTHDIHALI LGRAITGIQA FTASK

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q92947

Internal Search Terms :

GCDH, Glutaryl-CoA dehydrogenase, ACAD5, GCD, Glutaryl-CoA dehydrogenase, ACAD-5, ACAD 5,ATGP0622-10ug,ATGP0622-20ug,ATGP0622-50ug,ATGP0622-100ug,ATGP0622-250ug,ATGP0622-500ug,ATGP0622-1mg,ATGP0622-10,ATGP0622-20,ATGP0622-50,ATGP0622-100,ATGP0622-250,ATGP0622-500,ATGP0622-1

more info or order :

NKMAX product webpage